User profiles for Tim Lüddecke

Dr. Tim Lüddecke

Group Leader - Animal Venomics Lab at Fraunhofer IME-BR & LOEWE TBG
Verified email at ime.fraunhofer.de
Cited by 499

The biology and evolution of spider venoms

T Lüddecke, V Herzig, BM Von Reumont… - Biological …, 2022 - Wiley Online Library
Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million
years. They are well known for their complex venom systems that are used to overpower their …

[HTML][HTML] An Economic Dilemma between Molecular Weapon Systems May Explain an Arachno-Atypical Venom in Wasp Spiders (Argiope bruennichi)

T Lüddecke, BM von Reumont, F Förster, A Billion… - Biomolecules, 2020 - mdpi.com
Spiders use venom to subdue their prey, but little is known about the diversity of venoms in
different spider families. Given the limited data available for orb-weaver spiders (Araneidae), …

[HTML][HTML] Antiviral potential of natural resources against influenza virus infections

…, M Oberpaul, V Czudai-Matwich, T Lüddecke… - Viruses, 2022 - mdpi.com
Influenza is a severe contagious disease caused by influenza A and B viruses. The WHO
estimates that annual outbreaks lead to 3–5 million severe infections of which approximately 10…

A salamander's toxic arsenal: review of skin poison diversity and function in true salamanders, genus Salamandra

T Lüddecke, S Schulz, S Steinfartz, M Vences - The Science of Nature, 2018 - Springer
Terrestrial salamanders of the genus Salamandra represent one of the most prominent groups
of amphibians. They are mainly distributed across Europe but also reach Northern Africa …

Phylotranscriptomic evidence for pervasive ancient hybridization among Old World salamanders

…, W Babik, F Bossuyt, S Künzel, T Lüddecke… - Molecular Phylogenetics …, 2021 - Elsevier
Hybridization can leave genealogical signatures in an organism's genome, originating from
the parental lineages and persisting over time. This potentially confounds phylogenetic …

[HTML][HTML] Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research

…, MI Klapa, I Koludarov, J Kool, T Lüddecke… - …, 2022 - academic.oup.com
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …

Discovering the silk road: Nuclear and mitochondrial sequence data resolve the phylogenetic relationships among theraphosid spider subfamilies

T Lüddecke, H Krehenwinkel, G Canning… - Molecular phylogenetics …, 2018 - Elsevier
The mygalomorph spiders in the family Theraphosidae, also known as “tarantulas”, are one
of the most popular and diverse groups of arachnids, but their evolutionary history remains …

[HTML][HTML] Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides

J Krämer, T Lüddecke, M Marner, E Maiworm… - Toxins, 2022 - mdpi.com
Linear cationic venom peptides are antimicrobial peptides (AMPs) that exert their effects by
damaging cell membranes. These peptides can be highly specific, and for some, a significant …

[HTML][HTML] The pharmacological potential of novel melittin variants from the honeybee and solitary bees against inflammation and cancer

P Erkoc, BM von Reumont, T Lüddecke, M Henke… - Toxins, 2022 - mdpi.com
The venom of honeybees is composed of numerous peptides and proteins and has been
used for decades as an anti-inflammatory and anti-cancer agent in traditional medicine. …

[HTML][HTML] Venom biotechnology: casting light on nature's deadliest weapons using synthetic biology

T Lüddecke, A Paas, RJ Harris, L Talmann… - … in bioengineering and …, 2023 - frontiersin.org
Venoms are complex chemical arsenals that have evolved independently many times in the
animal kingdom. Venoms have attracted the interest of researchers because they are an …