Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems

…, B Steiert, M Schelker, C Kreutz, T Maiwald… - …, 2015 - academic.oup.com
Modeling of dynamical systems using ordinary differential equations is a popular approach
in the field of systems biology. Two of the most critical steps in this approach are to construct …

[HTML][HTML] PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure

M Pellegrini-Calace, T Maiwald… - PLoS computational …, 2009 - journals.plos.org
Transmembrane channel proteins play pivotal roles in maintaining the homeostasis and
responsiveness of cells and the cross-membrane electrochemical gradient by mediating the …

A Review of Integrated Systems and Components for 6G Wireless Communication in the -Band

T Maiwald, T Li, GR Hotopan, K Kolb… - Proceedings of the …, 2023 - ieeexplore.ieee.org
The evolution of wireless communication points to increasing demands on throughput for
data-intensive applications in modern society. Integrated millimeter-wave systems with …

[HTML][HTML] Driving the model to its limit: profile likelihood based model reduction

T Maiwald, H Hass, B Steiert, J Vanlier, R Engesser… - PloS one, 2016 - journals.plos.org
In systems biology, one of the major tasks is to tailor model complexity to information
content of the data. A useful model should describe the data and produce well-determined …

SiGe HBTs and BiCMOS technology for present and future millimeter-wave systems

…, H Hettrich, A Karakuzulu, T Maiwald… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
This paper gives an overall picture from BiCMOS technologies up to THz systems integration,
which were developed in the European Research project TARANTO. The European high …

Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

…, C Dächert, T Maiwald… - Molecular systems …, 2020 - embopress.org
Tightly interlinked feedback regulators control the dynamics of intracellular responses
elicited by the activation of signal transduction pathways. Interferon alpha (IFNα) orchestrates …

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α‐induced early antiviral signalling

T Maiwald, A Schneider, H Busch, S Sahle… - The FEBS …, 2010 - Wiley Online Library
Type I interferons (IFN) are important components of the innate antiviral response. A key
signalling pathway activated by IFNα is the Janus kinase/signal transducer and activator of …

Additive manufacturing of powdery Ni-based superalloys Mar-M-247 and CM 247 LC in hybrid laser metal deposition

…, T Finaske, A Straubel, H Wendrock, T Maiwald… - … Materials Transactions A, 2018 - Springer
The present paper addresses the phenomena of hot cracking of nickel-based superalloys in
the perspective of hybrid Laser Metal Deposition (combined application of induction and …

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

…, A Fulgham, A Boudot, T Maiwald… - Proceedings of the …, 2019 - National Acad Sciences
Activation of the Met receptor tyrosine kinase, either by its ligand, hepatocyte growth factor (HGF),
or via ligand-independent mechanisms, such as MET amplification or receptor …

Intrinsic heat treatment within additive manufacturing of gamma titanium aluminide space hardware

A Seidel, S Saha, T Maiwald, J Moritz, S Polenz… - Jom, 2019 - Springer
A major part of laser additive manufacturing focuses on the fabrication of metallic parts for
applications in the space and aerospace sectors. Especially, the processing of the very brittle …