[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …
the precision and sensitivity of evolutionary inference, producing more robust results than …
Functional and Evolutionary Insights from the Genomes of Three Parasitoid Nasonia Species
We report here genome sequences and comparative analyses of three closely related
parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important …
parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important …
[HTML][HTML] A scan for positively selected genes in the genomes of humans and chimpanzees
…, AG Clark, S Glanowski, TB Sackton… - PLoS …, 2005 - journals.plos.org
Since the divergence of humans and chimpanzees about 5 million years ago, these species
have undergone a remarkable evolution with drastic divergence in anatomy and cognitive …
have undergone a remarkable evolution with drastic divergence in anatomy and cognitive …
Dense sampling of bird diversity increases power of comparative genomics
Whole-genome sequencing projects are increasingly populating the tree of life and
characterizing biodiversity 1 , 2 , 3 – 4 . Sparse taxon sampling has previously been proposed to …
characterizing biodiversity 1 , 2 , 3 – 4 . Sparse taxon sampling has previously been proposed to …
Dynamic evolution of the innate immune system in Drosophila
The availability of complete genome sequence from 12 Drosophila species presents the
opportunity to examine how natural selection has affected patterns of gene family evolution and …
opportunity to examine how natural selection has affected patterns of gene family evolution and …
[HTML][HTML] Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment
Background Adult house flies, Musca domestica L., are mechanical vectors of more than 100
devastating diseases that have severe consequences for human and animal health. House …
devastating diseases that have severe consequences for human and animal health. House …
[HTML][HTML] Natural selection constrains neutral diversity across a wide range of species
The neutral theory of molecular evolution predicts that the amount of neutral polymorphisms
within a species will increase proportionally with the census population size (Nc). However, …
within a species will increase proportionally with the census population size (Nc). However, …
Evolution of protein-coding genes in Drosophila
Several contributing factors have been implicated in evolutionary rate heterogeneity among
proteins, but their evolutionary mechanisms remain poorly characterized. The recently …
proteins, but their evolutionary mechanisms remain poorly characterized. The recently …
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C
KL Sackton, N Dimova, X Zeng, W Tian, M Zhang… - Nature, 2014 - nature.com
Protein machines are multi-subunit protein complexes that orchestrate highly regulated
biochemical tasks. An example is the anaphase-promoting complex/cyclosome (APC/C), a 13-…
biochemical tasks. An example is the anaphase-promoting complex/cyclosome (APC/C), a 13-…
Convergent regulatory evolution and loss of flight in paleognathous birds
A core question in evolutionary biology is whether convergent phenotypic evolution is
driven by convergent molecular changes in proteins or regulatory regions. We combined …
driven by convergent molecular changes in proteins or regulatory regions. We combined …