User profiles for Timothy Beck

Timothy Beck

Research Engineer, CDC-NIOSH
Verified email at cdc.gov
Cited by 264

Genomic hallmarks of localized, non-indolent prostate cancer

…, E Lalonde, M Ahmed, D Trudel, X Luo, TA Beck… - Nature, 2017 - nature.com
Prostate tumours are highly variable in their response to therapies, but clinically available
prognostic factors can explain only a fraction of this heterogeneity. Here we analysed 200 …

Spatial genomic heterogeneity within localized, multifocal prostate cancer

…, NS Fox, J Livingstone, YJ Shiah, J Wang, TA Beck… - Nature …, 2015 - nature.com
Herein we provide a detailed molecular analysis of the spatial heterogeneity of clinically
localized, multifocal prostate cancer to delineate new oncogenes or tumor suppressors. We …

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

…, AMK Brown, JC Kim, T Wang, JT Simpson, T Beck… - Nature, 2016 - nature.com
Pancreatic cancer, a highly aggressive tumour type with uniformly poor prognosis,
exemplifies the classically held view of stepwise cancer development 1 . The current model of …

[HTML][HTML] A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

…, MD Eldridge, E Hovig, LE Heisler, TA Beck… - Nature …, 2015 - nature.com
As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full
understanding of the variables affecting sequencing analysis output is required. Here using …

Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

…, E Hutton, E Tseng, CS Chin, T Beck… - Genome …, 2018 - genome.cshlp.org
The SK-BR-3 cell line is one of the most important models for HER2+ breast cancers, which
affect one in five breast cancer patients. SK-BR-3 is known to be highly rearranged, although …

[HTML][HTML] Mapping of clinical management resources for snakebites and other animal envenomings in the Brazilian Amazon

TP Beck, A Tupetz, AS Farias, A Silva-Neto, T Rocha… - Toxicon: X, 2022 - Elsevier
Snakebite envenomings (SBEs) and other envenomings triggered by venomous animals (VAEs)
represent a significant disease burden in Brazil, with 29,152 SBEs reported in 2021 …

[HTML][HTML] Design of a water curtain to reduce accumulations of float coal dust in longwall returns

CE Seaman, MR Shahan, TW Beck… - International journal of …, 2020 - Elsevier
Accumulation of float coal dust (FCD) in underground mines is an explosion hazard that affects
all underground coal mine workers. While this hazard is addressed by the application of …

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer‐associated variants

…, M Volar, M Chan‐Seng‐Yue, T Beck… - … journal of cancer, 2014 - Wiley Online Library
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with
colorectal cancer (CRC) in a genome‐wide association study; this finding has been replicated …

[PDF][PDF] Instrumentation practice for slope monitoring

WF Kane, TJ Beck - … practice in Northern California. Association of …, 2000 - academia.edu
Remote monitoring of slope movement using electronic instrumentation can be an effective
approach for many unstable or potentially unstable slopes. Water levels can be observed …

A phenomenological analysis of anxiety as experienced in social situations

TJ Beck - Journal of Phenomenological Psychology, 2013 - brill.com
In this study, three individual descriptions of anxiety as experienced in social situations
were analyzed so that a general structure representing social anxiety could potentially be …