Epithelial cancers are believed to originate from transformation of tissue stem cells. However,
bone marrow–derived cells (BMDCs), which are frequently recruited to sites of tissue injury …

The construction of thousands of well-defined, porous, metal–organic framework (MOF)
structures, spanning a broad range of topologies and an even broader range of pore sizes and …

Cancer stem cells (CSCs) have been defined as a unique subpopulation in tumors that possess
the ability to initiate tumor growth and sustain tumor self-renewal. Although the evidence …

PHYSICAL associations between cyclins, viral oncogenes and tumour suppressor genes
imply a central role for cyclins in growth control 1, 2 . Cyclin D1 was identified as a candidate …

Carcinoma-associated fibroblasts (CAFs) that express α-smooth muscle actin (αSMA)
contribute to cancer progression, but their precise origin and role are unclear. Using mouse …

The association between chronic inflammation and cancer is now well established. This
association has recently received renewed interest with the recognition that microbial …

Polymorphisms of interleukin-1β (IL-1β) are associated with an increased risk of solid
malignancies. Here, we show that stomach-specific expression of human IL-1β in transgenic mice …

The stem cells that maintain and repair the postnatal skeleton remain undefined. One model
suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, …

Background & Aims: Hypergastrinemia occurs frequently in association with acid suppression
and Helicobacter infection, but its role in the progression to gastric atrophy and gastric …

There is growing evidence that tumors are sustained and promoted by inflammatory signals
from the surrounding microenvironment. Two papers by Grivennikov et al. and Bollrath et al. …