User profiles for Timothy E. Holy
Timothy E. HolyWashington University in St. Louis Verified email at wustl.edu Cited by 6252 |
Loss of sex discrimination and male-male aggression in mice deficient for TRP2
The mouse vomeronasal organ (VNO) is thought to mediate social behaviors and neuroendocrine
changes elicited by pheromonal cues. The molecular mechanisms underlying the …
changes elicited by pheromonal cues. The molecular mechanisms underlying the …
[HTML][HTML] Ultrasonic songs of male mice
TE Holy, Z Guo - PLoS biology, 2005 - journals.plos.org
Previously it was shown that male mice, when they encounter female mice or their pheromones,
emit ultrasonic vocalizations with frequencies ranging over 30–110 kHz. Here, we show …
emit ultrasonic vocalizations with frequencies ranging over 30–110 kHz. Here, we show …
Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language
In 2001, a point mutation in the forkhead box P2 (FOXP2) coding sequence was identified as
the basis of an inherited speech and language disorder suffered by members of the family …
the basis of an inherited speech and language disorder suffered by members of the family …
[PDF][PDF] Fast three-dimensional fluorescence imaging of activity in neural populations by objective-coupled planar illumination microscopy
Unraveling the functions of the diverse neural types in any local circuit ultimately requires
methods to record from most or all of its cells simultaneously. One promising approach to this …
methods to record from most or all of its cells simultaneously. One promising approach to this …
Dynamic instability of microtubules as an efficient way to search in space.
TE Holy, S Leibler - … of the National Academy of Sciences, 1994 - National Acad Sciences
During the formation of the mitotic spindle, dynamic microtubules search for chromosomes
in the surrounding cytosol. The average time required to reach such "targets" is calculated …
in the surrounding cytosol. The average time required to reach such "targets" is calculated …
Responses of vomeronasal neurons to natural stimuli
The vomeronasal organ (VNO) of mammals plays an essential role in the detection of
pheromones. We obtained simultaneous recordings of action potentials from large subsets of VNO …
pheromones. We obtained simultaneous recordings of action potentials from large subsets of VNO …
[PDF][PDF] Physiologic diversity and development of intrinsically photosensitive retinal ganglion cells
Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate numerous nonvisual
phenomena, including entrainment of the circadian clock to light-dark cycles, pupillary light …
phenomena, including entrainment of the circadian clock to light-dark cycles, pupillary light …
[HTML][HTML] Julia for biologists
Major computational challenges exist in relation to the collection, curation, processing and
analysis of large genomic and imaging datasets, as well as the simulation of larger and more …
analysis of large genomic and imaging datasets, as well as the simulation of larger and more …
Assembly and positioning of microtubule asters in microfabricated chambers
Intracellular organization depends on a variety of molecular assembly processes; while some
of these have been studied in simplified cell-free systems, others depend on the confined …
of these have been studied in simplified cell-free systems, others depend on the confined …
Sulfated steroids as natural ligands of mouse pheromone-sensing neurons
Among mice, pheromones and other social odor cues convey information about sex, social
status, and identity; however, the molecular nature of these cues is essentially unknown. To …
status, and identity; however, the molecular nature of these cues is essentially unknown. To …