[HTML][HTML] Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks
TH Helms, RD Mullins, JM Thomas-Ahner, SK Kulp… - Scientific Reports, 2021 - nature.com
A promotional role for androgen receptor (AR) signaling in hepatocellular carcinogenesis is
emerging. In pre-clinical models, including diethylnitrosamine- (DEN-) induced …
emerging. In pre-clinical models, including diethylnitrosamine- (DEN-) induced …
[HTML][HTML] Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store …
Gain-of-function mutations in the human Ca V 2.1 gene CACNA1A cause familial hemiplegic
migraine type 1 (FHM1). To characterize cellular problems potentially triggered by Ca V 2.1 …
migraine type 1 (FHM1). To characterize cellular problems potentially triggered by Ca V 2.1 …
Murine cancer cachexia models replicate elevated catabolic pembrolizumab clearance in humans
…, UL Subrayan, T Costa, TH Helms… - JCSM Rapid …, 2021 - Wiley Online Library
Background Monoclonal antibody (mAb) immune checkpoint inhibitor (ICI) therapies have
dramatically impacted oncology this past decade. However, only about one‐third of patients …
dramatically impacted oncology this past decade. However, only about one‐third of patients …
Use of doxorubicin chemotherapy following debulking surgery in the treatment of a cat with mesenteric hemangiosarcoma
…, ME Long, JA Hokamp, TH Helms… - Journal of Feline …, 2022 - journals.sagepub.com
Case summary A 7-year-old male castrated domestic shorthair cat presented with a 5-day
history of inappetence. A mid-abdominal mass was palpated and, on exploratory laparotomy, …
history of inappetence. A mid-abdominal mass was palpated and, on exploratory laparotomy, …
Ischemic necrosis of the digits and hyperlipidemia associated with atherosclerosis in a Miniature American Shepherd
…, JD Bonagura, RA Kohnken, TH Helms… - Journal of the …, 2018 - Am Vet Med Assoc
CASE DESCRIPTION A 2.5-year-old 12-kg (26.4-lb) castrated male Miniature American
Shepherd was referred because of a 3-week history of a localized crusted skin lesion on the …
Shepherd was referred because of a 3-week history of a localized crusted skin lesion on the …
SAT005 Effect Of OSU-ERβ-12, A Carborane-based ERβ-selective Agonist, On Hepatic Fibrosis And NASH
P Kumar, TH Helms, H Radomska… - Journal of the …, 2023 - academic.oup.com
… Anti-fibrotic activity of ERβ-12 was assessed in vitro in a human HCC cell (HepG2)/human
HSC (LX-2) co-culture system treated with ERβ-12, TGFβ or the combination for 24 h. …
HSC (LX-2) co-culture system treated with ERβ-12, TGFβ or the combination for 24 h. …
Exploiting Sexual Dimorphism in Liver Disease: Targeting Sex Hormone Signaling to Treat Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma
TH Helms - 2021 - rave.ohiolink.edu
Therapeutic estrogens address multiple facets of non-alcoholic steatohepatitis (NASH)
pathophysiology. Their potential, however, is limited by undesirable side effects caused by …
pathophysiology. Their potential, however, is limited by undesirable side effects caused by …
Spouses' gender role attitudes, wives' employment status, and Mexican-origin husbands' marital satisfaction
ND Hengstebeck, HM Helms… - Journal of Family …, 2015 - journals.sagepub.com
Informed by Peplau’s theory of roles, this study examined the complex interplay between
spouses’ gender role attitudes and wives’ employment status as a predictor of Mexican-origin …
spouses’ gender role attitudes and wives’ employment status as a predictor of Mexican-origin …
[BOOK][B] Textbook of therapeutics: drug and disease management
RA Helms, DJ Quan - 2006 - books.google.com
This popular text continues to help healthcare professionals and students master the basics
of therapeutics. Distinguished experts deliver in-depth information on the latest drug …
of therapeutics. Distinguished experts deliver in-depth information on the latest drug …
Financial Institutions Reform, Recovery, and Enforcement Act: An Ethical Quagmire for Attorneys Representing Financial Institutions
HB Helms - Wake Forest L. Rev., 1992 - HeinOnline
[I] t is in the public interest for banks and thrifts to have qualified and competent people
directing the affairs of financial institutions. Likewise, it is sound public policy to hold these high …
directing the affairs of financial institutions. Likewise, it is sound public policy to hold these high …