Objective: Our purpose was to review our experience with fetal congenital cystic adenomatoid
malformation and extralobar pulmonary sequestration emphasizing natural history, …

Background/Purpose: Cystic adenomatoid malformation of the lung (CAM) diagnosed in utero
has a variable natural history that may result in hydrops in up to 40% or regress in up to 15…

ContextHindbrain herniation occurs in a large percentage of children with myelomeningocele
and is the leading cause of death in this population. The effect of early fetal closure of …

Background: The EXIT (ex utero intrapartum treatment) procedure, although initially designed
for reversal of tracheal occlusion in fetuses with congenital diaphragmatic hernias (CDH), …

The mechanisms that underlie the lack of scarring in fetal wounds are unknown, but probably
relate to the control of collagen fibrillogenesis. The role of collagen in the fetal wound …

PURPOSE: To understand the natural history and define indications for fetal intervention in
sacrococcygeal teratoma (SCT), the authors reviewed all cases of fetal SCT presenting for …

In-utero spina bifida repair Panel A= exposure of 23-week gestation fetus through hysterotomy
revealing spina bifida defect (arrow). Panel B= closure of skin flaps over the spinal cord; a …

Fetal wound healing is characterized by minimal inflammation and scarless repair. IL-6
stimulates inflammation in postnatal wound healing. We hypothesized that fetal skin has a …

Primary fetal hydrothorax presents a wide spectrum of severity ranging from small, harmless
effusions, to life-threatening thoracic compression. To define natural history and …

Background: Fetal dermal wound healing is characterized by minimal inflammation,
restoration of normal dermal architecture, and scarless repair. The authors have shown that …