User profiles for Timothy Moural

Timothy Moural

Assistant Research Professor, Penn State University
Verified email at psu.edu
Cited by 741

[HTML][HTML] Functional and structural diversity of insect glutathione S-transferases in xenobiotic adaptation

SK BK, T Moural, F Zhu - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
As a superfamily of multifunctional enzymes that is mainly associated with xenobiotic adaptation,
glutathione S-transferases (GSTs) facilitate insects' survival under chemical stresses in …

[HTML][HTML] Integrated analysis of cytochrome P450 gene superfamily in the red flour beetle, Tribolium castaneum

F Zhu, TW Moural, K Shah, SR Palli - BMC genomics, 2013 - Springer
Background The functional and evolutionary diversification of insect cytochrome P450s (CYPs)
shaped the success of insects. CYPs constitute one of the largest and oldest gene …

[HTML][HTML] A specialist herbivore pest adaptation to xenobiotics through up-regulation of multiple Cytochrome P450s

F Zhu, TW Moural, DR Nelson, SR Palli - Scientific reports, 2016 - nature.com
The adaptation of herbivorous insects to their host plants is hypothesized to be intimately
associated with their ubiquitous development of resistance to synthetic pesticides. However, …

Mechanisms and management of acaricide resistance for Tetranychus urticae in agroecosystems

AW Adesanya, MD Lavine, TW Moural, LC Lavine… - Journal of Pest …, 2021 - Springer
The two-spotted spider mite, Tetranychus urticae Koch, is a constant threat to sustainable
production of numerous economically important crops globally. Management of T. urticae is …

[HTML][HTML] Dynamic roles of insect carboxyl/cholinesterases in chemical adaptation

C Cruse, TW Moural, F Zhu - Insects, 2023 - mdpi.com
Simple Summary Carboxyl/cholinesterases (CCEs) represent a family of enzymes distributed
in many organisms, including insects. Despite their relatively simple catalyzed hydrolysis …

Characterization of class III peroxidases from switchgrass

TW Moural, KM Lewis, C Barnaba, F Zhu… - Plant …, 2017 - academic.oup.com
Class III peroxidases (CIIIPRX) catalyze the oxidation of monolignols, generate radicals, and
ultimately lead to the formation of lignin. In general, CIIIPRX genes encode a large number …

Odorant degrading carboxylesterases modulate foraging and mating behaviors of Grapholita molesta

H Wei, S Tan, Z Li, J Li, TW Moural, F Zhu, X Liu - Chemosphere, 2021 - Elsevier
Odorant degrading carboxylesterases (CXEs) play key roles in the process of odor signal
reception via degrading ester odorants. But the functional mechanisms of CXEs in modulating …

Physiological functions of a methuselah-like G protein coupled receptor in Lymantria dispar Linnaeus

C Cao, L Sun, H Du, TW Moural, H Bai, P Liu… - Pesticide biochemistry …, 2019 - Elsevier
Insect G protein coupled receptors (GPCRs) have been identified as a highly attractive
target for new generation insecticides discovery due to their critical physiological functions. …

Glutaredoxins and thioredoxin peroxidase involved in defense of emamectin benzoate induced oxidative stress in Grapholita molesta

Y Liu, F Zhu, Z Shen, TW Moural, L Liu, Z Li… - Pesticide Biochemistry …, 2021 - Elsevier
Glutaredoxins (Grxs) and thioredoxin peroxidases (Tpxs) are major antioxidant enzyme families
involved in regulating cellular redox homeostasis and in defense of enhanced oxidative …

[HTML][HTML] Structural and Functional Characterization of One Unclassified Glutathione S-Transferase in Xenobiotic Adaptation of Leptinotarsa decemlineata

Y Liu, T Moural, S Koirala BK, J Hernandez… - International journal of …, 2021 - mdpi.com
Arthropod Glutathione S-transferases (GSTs) constitute a large family of multifunctional
enzymes that are mainly associated with xenobiotic or stress adaptation. GST-mediated …