Reduced Vancomycin Susceptibility in Staphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains …

…, JK Davies, PDR Johnson, TP Stinear… - Clinical microbiology …, 2010 - Am Soc Microbiol
The emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous
vancomycin-intermediate Staphylococcus aureus (hVISA) over the past decade has …

[HTML][HTML] Staphylococcus aureus host interactions and adaptation

…, JYH Lee, A Hachani, IR Monk, TP Stinear - Nature Reviews …, 2023 - nature.com
Invasive Staphylococcus aureus infections are common, causing high mortality, compounded
by the propensity of the bacterium to develop drug resistance. S. aureus is an excellent …

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

TP Stinear, T Seemann, PF Harrison… - Genome …, 2008 - genome.cshlp.org
Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of
Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the …

Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer

TP Stinear, T Seemann, S Pidot, W Frigui… - Genome …, 2007 - genome.cshlp.org
Mycobacterium ulcerans is found in aquatic ecosystems and causes Buruli ulcer in humans,
a neglected but devastating necrotic disease of subcutaneous tissue that is rampant …

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

TP Stinear, A Mve-Obiang, PLC Small… - Proceedings of the …, 2004 - National Acad Sciences
Mycobacterium ulcerans (MU), an emerging human pathogen harbored by aquatic insects,
is the causative agent of Buruli ulcer, a devastating skin disease rife throughout Central and …

[HTML][HTML] Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR

…, JK Davies, T Seemann, TP Stinear - PLoS …, 2011 - journals.plos.org
Antimicrobial resistance in Staphylococcus aureus is a major public health threat, compounded
by emergence of strains with resistance to vancomycin and daptomycin, both last line …

[HTML][HTML] Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

…, MC Gutierrez, C Leclerc, SD Bentley, TP Stinear… - Nature …, 2013 - nature.com
Global spread and limited genetic variation are hallmarks of M. tuberculosis, the agent of
human tuberculosis. In contrast, Mycobacterium canettii and related tubercle bacilli that also …

[HTML][HTML] Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia

…, CJ Lavender, E Wishart, TP Stinear… - Emerging infectious …, 2007 - ncbi.nlm.nih.gov
Buruli ulcer (BU) occurs in> 30 countries. The causative organism, Mycobacterium ulcerans,
is acquired from the environment, but the exact mode of transmission is unknown. We …

[HTML][HTML] Tracking the COVID-19 pandemic in Australia using genomics

…, T Hoang, M Easton, S Dougall, TP Stinear… - Nature …, 2020 - nature.com
Genomic sequencing has significant potential to inform public health management for SARS-CoV-2.
Here we report high-throughput genomics for SARS-CoV-2, sequencing 80% of …

Isolates with Low-Level Vancomycin Resistance Associated with Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia

…, PDR Johnson, PB Ward, TP Stinear… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Low-level vancomycin-resistant Staphylococcus aureus (vancomycin-intermediate S. aureus
[VISA] and heterogenous VISA [hVISA]) is increasingly reported and leads to glycopeptide …