User profiles for Timothy P. Jenkins
Timothy P. JenkinsHead of Data Science and Assistant Professor at DTU Bioengineering Verified email at dtu.dk Cited by 1470 |
[HTML][HTML] Bee updated: current knowledge on bee venom and bee envenoming therapy
Honey bees can be found all around the world and fulfill key pollination roles within their
natural ecosystems, as well as in agriculture. Most species are typically docile, and most …
natural ecosystems, as well as in agriculture. Most species are typically docile, and most …
[HTML][HTML] Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes
Snakebite envenoming continues to claim many lives across the globe, necessitating the
development of improved therapies. To this end, broadly-neutralizing human monoclonal …
development of improved therapies. To this end, broadly-neutralizing human monoclonal …
[HTML][HTML] Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition
TP Jenkins, Y Rathnayaka, PK Perera, LE Peachey… - PLoS …, 2017 - journals.plos.org
Investigations of the impact that patent infections by soil-transmitted gastrointestinal nematode
parasites exert on the composition of the host gut commensal flora are attracting growing …
parasites exert on the composition of the host gut commensal flora are attracting growing …
Assessing developability early in the discovery process for novel biologics
Beyond potency, a good developability profile is a key attribute of a biological drug.
Selecting and screening for such attributes early in the drug development process can save …
Selecting and screening for such attributes early in the drug development process can save …
This gut ain't big enough for both of us. Or is it? Helminth–microbiota interactions in veterinary species
LE Peachey, TP Jenkins, C Cantacessi - Trends in parasitology, 2017 - cell.com
Gastrointestinal helminth parasites share their habitat with a myriad of other organisms, that
is, the commensal microbiota. Increasing evidence, particularly in humans and rodent …
is, the commensal microbiota. Increasing evidence, particularly in humans and rodent …
[HTML][HTML] Animal immunization, in vitro display technologies, and machine learning for antibody discovery
…, A Karatt-Vellatt, S Muyldermans, TP Jenkins - Trends in …, 2021 - cell.com
For years, a discussion has persevered on the benefits and drawbacks of antibody discovery
using animal immunization versus in vitro selection from non-animal-derived recombinant …
using animal immunization versus in vitro selection from non-animal-derived recombinant …
[HTML][HTML] Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota
In spite of the extensive contribution of intestinal pathology to the pathophysiology of
schistosomiasis, little is known of the impact of schistosome infection on the composition of the gut …
schistosomiasis, little is known of the impact of schistosome infection on the composition of the gut …
[HTML][HTML] Heterochronic faecal transplantation boosts gut germinal centres in aged mice
…, A Silva-Cayetano, S Innocentin, TP Jenkins… - Nature …, 2019 - nature.com
Ageing is a complex multifactorial process associated with a plethora of disorders, which
contribute significantly to morbidity worldwide. One of the organs significantly affected by age is …
contribute significantly to morbidity worldwide. One of the organs significantly affected by age is …
[HTML][HTML] The rise of genomics in snake venom research: recent advances and future perspectives
…, L Seneci, M Mousavi-Derazmahalleh, TP Jenkins… - …, 2022 - academic.oup.com
Snake venoms represent a danger to human health, but also a gold mine of bioactive proteins
that can be harnessed for drug discovery purposes. The evolution of snakes and their …
that can be harnessed for drug discovery purposes. The evolution of snakes and their …
[HTML][HTML] Changes in duodenal tissue-associated microbiota following hookworm infection and consecutive gluten challenges in humans with coeliac disease
A reduced diversity of the gastrointestinal commensal microbiota is associated with the
development of several inflammatory diseases. Recent reports in humans and animal models …
development of several inflammatory diseases. Recent reports in humans and animal models …