Although there is evidence that redox regulation has an essential role in malignancies, its
impact on tumor prognosis remains unclear. Here we show crosstalk between oxidative stress …

Understanding the tumor immune microenvironment (TIME) promises to be key for optimal
cancer therapy, especially in triple-negative breast cancer (TNBC). Integrating spatial …

Stromal stiffening accompanies malignancy, compromises treatment and promotes tumour
aggression. Clarifying the molecular nature and the factors that regulate stromal stiffening in …

The extent of tumor-infiltrating lymphocytes (TILs), along with immunomodulatory ligands,
tumor-mutational burden and other biomarkers, has been demonstrated to be a marker of …

Background Recent efforts of gene expression profiling analyses recognized at least four
different triple-negative breast cancer (TNBC) molecular subtypes. However, little is known …

Anti‐cancer drugs often increase reactive oxygen species ( ROS ) and cause DNA damage.
Here, we highlight a new cross talk between chronic oxidative stress and the histone variant …

Stromal tumor-infiltrating lymphocytes (sTILs) are important prognostic and predictive
biomarkers in triple-negative (TNBC) and HER2-positive breast cancer. Incorporating sTILs into …

Infiltration of C D 8 + T lymphocytes into solid tumors is associated with good prognosis in
various types of cancer, including triple-negative breast cancer (TNBC). However, the …

The role of the stromal compartment in tumor progression is best illustrated in breast cancer
bone metastases, where the stromal compartment supports tumor growth, albeit through …

Ovarian cancer is a silent disease with a poor prognosis that urgently requires new
therapeutic strategies. In low-grade ovarian tumours, mutations in the MAP3K BRAF gene …