User profiles for Ting Fung Chan

Ting-Fung Chan

School of Life Sciences, The Chinese University of Hong Kong
Verified email at cuhk.edu.hk
Cited by 8624

[HTML][HTML] Terpenes and terpenoids in plants: Interactions with environment and insects

…, SSK Tsang, C Li, IHT Lee, HM Lam, TF Chan… - International Journal of …, 2020 - mdpi.com
The interactions of plants with environment and insects are bi-directional and dynamic.
Consequently, a myriad of mechanisms has evolved to engage organisms in different types of …

[HTML][HTML] Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing

…, F Zhou, TH Phang, X Liu, SW Tong, TF Chan… - Nature …, 2014 - nature.com
Using a whole-genome-sequencing approach to explore germplasm resources can serve as
an important strategy for crop improvement, especially in investigating wild accessions that …

[PDF][PDF] Viral-human chimeric transcript predisposes risk to liver cancer development and progression

…, JHM Tong, PBS Lai, HLY Chan, KF To, TF Chan… - Cancer cell, 2014 - cell.com
The mutagenic effect of hepatitis B (HBV) integration in predisposing risk to hepatocellular
carcinoma (HCC) remains elusive. In this study, we performed transcriptome sequencing of …

Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs

…, SC Sze, X Ding, NN Co, SM Ngai, TF Chan… - …, 2015 - academic.oup.com
Exosomes are increasingly recognized as important mediators of cell–cell communication in
cancer progression through the horizontal transfer of RNAs and proteins to neighboring or …

[HTML][HTML] Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases

…, JH Choi, J Carvalho, W Ai, C Zeng, TF Chan… - Journal of Biological …, 2000 - ASBMB
Gln3p is a GATA-type transcription factor responsive to different nitrogen nutrients and starvation
in yeastSaccharomyces cerevisiae. Recent evidence has linked TOR signaling to Gln3p…

[HTML][HTML] A reference-grade wild soybean genome

…, HT Nguyen, SB Cannon, CH Foyer, TF Chan… - Nature …, 2019 - nature.com
Efficient crop improvement depends on the application of accurate genetic information
contained in diverse germplasm resources. Here we report a reference-grade genome of wild …

[HTML][HTML] Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation

…, J Wang, RCW Ma, SKW Tsui, JCN Chan, TF Chan… - Genome biology, 2014 - Springer
Background DNA methylation is an important type of epigenetic modification involved in
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …

Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma

…, NN Co, M He, RWM Lung, AWH Chan, TF Chan… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Small non-coding RNAs (ncRNA) are increasingly recognized to
play important roles in tumorigenesis. With the advent of deep sequencing, efforts have been …

[HTML][HTML] The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens

TF Chan, KM Ji, AKY Yim, XY Liu, JW Zhou… - Journal of Allergy and …, 2015 - Elsevier
Background A sequenced house dust mite (HDM) genome would advance our understanding
of HDM allergens, a common cause of human allergies. Objective We sought to produce …

RNA G-quadruplexes (rG4s): genomics and biological functions

K Lyu, EYC Chow, X Mou, TF Chan… - Nucleic acids …, 2021 - academic.oup.com
G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that have been
first observed decades ago. Over the years, these four-stranded structural motifs have been …