Cell penetrating peptides (CPPs) can deliver cell-impermeable therapeutic cargos into cells.
In particular, CPP-cargo conjugates tend to accumulate inside cells by endocytosis. …

We report that a tetramethylrhodamine-labeled dimer of the cell-penetrating peptide TAT,
dfTAT, penetrates live cells by escaping from endosomes with high efficiency. By mediating …

Carbon dots are admirable fluorescent nanomaterials due to their low cost, high photostability,
excellent biocompatibility, and environmental friendliness. Most conventional carbon dot …

Infectious diseases were one of the major causes of mortality until now because drug-resistant
bacteria have arisen under broad use and abuse of antibacterial drugs. These multidrug-…

Cell delivery or cell killing processes often involve the crossing or disruption of cellular
membranes. We review how, by modifying the composition and properties of membranes, …

With the brain's limited capacity for repair there is a need for new and innovative therapies
to promote regeneration. Stem/progenitor cell transplantation has received increasing …

Stem cell transplants offer significant hope for brain repair following ischemic damage. Pre-clinical
work suggests that therapeutic mechanisms may be multi-faceted, incorporating bone-…

OBJECTIVES: This study assessed the effectiveness, adverse events, patient adherence,
and costs of modified dual therapy compared with bismuth-containing quadruple therapy for …

With the brain's limited capacity for repair, new and innovative approaches are required to
promote regeneration. While neural transplantation for a number of neural disease/injuries …

Endosomal entrapment is a severely limiting bottleneck in the delivery of biologics into cells.
The compound dfTAT was recently found to circumvent this problem by mediating …