[HTML][HTML] Massively multiplexed nucleic acid detection with Cas13

…, SH Ye, CK Boehm, TSF Kosoko-Thoroddsen… - Nature, 2020 - nature.com
The great majority of globally circulating pathogens go undetected, undermining patient care
and hindering outbreak preparedness and response. To enable routine surveillance and …

[HTML][HTML] Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

…, BM Shaw, G Adams, TSF Kosoko-Thoroddsen… - Nature …, 2020 - nature.com
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for
controlling disease transmission. Here, we develop SHINE (Streamlined Highlighting of …

[HTML][HTML] Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants

…, ME Grunberg, TSF Kosoko-Thoroddsen… - Nature biomedical …, 2022 - nature.com
The widespread transmission and evolution of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) call for rapid nucleic acid diagnostics that are easy to use outside of …

CRISPR-based surveillance for COVID-19 using genomically-comprehensive machine learning design

HC Metsky, CA Freije, TSF Kosoko-Thoroddsen… - BioRxiv, 2020 - biorxiv.org
The emergence and outbreak of SARS-CoV-2, the causative agent of COVID-19, has rapidly
become a global concern and has highlighted the need for fast, sensitive, and specific tools …

[PDF][PDF] CRISPR-based COVID-19 surveillance using a genomically-comprehensive machine learning approach

HC Metsky, CA Freije, TSF Kosoko-Thoroddsen… - BioRxiv, 2020 - biorxiv.org
The emergence and outbreak of SARS-CoV-2, the causative agent of COVID-19, has rapidly
become a global concern and has highlighted the need for fast, sensitive, and specific …

[HTML][HTML] Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2

…, BM Shaw, G Adams, TSF Kosoko-Thoroddsen… - BioRxiv, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for
controlling disease transmission. Here, we develop SHINE (SHERLOCK and HUDSON …

[HTML][HTML] Equipment-free detection of SARS-CoV-2 and Variants of Concern using Cas13

…, CA Freije, ME Grunberg, TSF Kosoko-Thoroddsen… - medrxiv, 2021 - ncbi.nlm.nih.gov
The COVID-19 pandemic, and the recent rise and widespread transmission of SARS-CoV-2
Variants of Concern (VOCs), have demonstrated the need for ubiquitous nucleic acid testing …

Use of Socioeconomic Demographic Data in Studies on Pediatric Unilateral Hearing Loss: A Scoping Review

AL Zhang, TSF Kosoko-Thoroddsen, DA Thomas… - Ear and …, 2024 - journals.lww.com
Objectives: Social determinants of health (SDOH)(healthcare access and quality, education
access and quality, socioeconomic status, social and cultural context, neighborhood and …

CRISPR-based assays for point of need detection and subtyping of influenza

…, J Arizti Sanz, AD Bradley, TSF Kosoko-Thoroddsen… - medRxiv, 2023 - medrxiv.org
The high disease burden of influenza virus poses a significant threat to human health and
requires better methods to rapidly detect its many circulating species, subtypes, and variants. …

Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2 (preprint)

…, BM Shaw, G Adams, TSF Kosoko-Thoroddsen… - 2020 - pesquisa.bvsalud.org
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for
controlling disease transmission. Here, we develop SHINE (SHERLOCK and HUDSON …