[PDF][PDF] Enzyme-constrained models and omics analysis of Streptomyces coelicolor reveal metabolic changes that enhance heterologous production

S Sulheim, T Kumelj, D van Dissel… - Iscience, 2020 - cell.com
Many biosynthetic gene clusters (BGCs) require heterologous expression to realize their
genetic potential, including silent and metagenomic BGCs. Although the engineered …

Predicting Strain Engineering Strategies Using iKS1317: A Genome‐Scale Metabolic Model of Streptomyces coelicolor

T Kumelj, S Sulheim, A Wentzel… - Biotechnology …, 2019 - Wiley Online Library
Streptomyces coelicolor is a model organism for the Actinobacteria, a phylum known to
produce an extensive range of different bioactive compounds that include antibiotics currently …

[HTML][HTML] Genome-scale metabolic modelling when changes in environmental conditions affect biomass composition

C Schulz, T Kumelj, E Karlsen… - PLoS Computational …, 2021 - journals.plos.org
Genome-scale metabolic modeling is an important tool in the study of metabolism by enhancing
the collation of knowledge, interpretation of data, and prediction of metabolic capabilities…

Genome-scale Model Constrained by Proteomics Reveals Metabolic Changes in Streptomyces coelicolor M1152 Compared to M145

S Sulheim, T Kumelj, D van Dissel… - bioRxiv, 2019 - biorxiv.org
Many biosynthetic gene clusters (BGCs) in the genomes of environmental microorganisms
require heterologous expression in order to realize their genetic potential, including cryptic …

[PDF][PDF] Genomescale model constrained by proteomics reveals metabolic rearrangements in the heterologous host streptomyces coelicolor

S Sulheim, T Kumelj, D Van Dissel… - bioRxiv, 2019 - researchgate.net
Streptomyces coelicolor M1152 is a widely used host strain for the heterologous production
of novel small molecule natural products, genetically engineered for this purpose through eg …

Genome-scale models and consequences of mass constraints and availability of enzymes

T Kumelj - 2021 - ntnuopen.ntnu.no
Genome-scale metabolic reconstructions offer a system-level view of metabolic networks
with genetic basis and suggest mechanistic determination of cell's physiological homeostatic …

[PDF][PDF] 2. Slovenski Geološki Kongres Idrija, 26.-28. september 2006

B Režun - Geologija, 2006 - geologija-revija.si
Po našem prvem srečanju v Črni na Koroškem pred štirimi leti, smo se v Idriji na gradu
Gewerkenegg ponovno zbrali slovenski geologi na 2. državnem kongresu. Organizatorja …

Preliminary tritium isoscape of precipitation across the Adriatic-Pannonian realm

Z Kern, IG Hatvani, T Kanduč, M Štrok, I Forisz… - 2018 - fulir.irb.hr
Tritium is an important natural tracer in the hydrological sciences. Measurements of the tritium
activity of precipitation in the Adriatic-Pannonian region began in Vienna Hohe Warte in …

[PDF][PDF] Results of the January 2016 waterbird census in Slovenia

L Božič - Acrocephalus, 2016 - sciendo.com
Januarsko štetje vodnih ptic (IWC) poteka v Sloveniji od leta 1988, leta 1997 pa je bilo prvič
zastavljeno kot celosten, koordiniran in standardiziran popis vodnih ptic na ozemlju celotne …

[PDF][PDF] Results of the January 2021 waterbird census in Slovenia

L Božič - Acrocephalus, 2020 - sciendo.com
Januar 2021 je bil v Sloveniji za 0, 8 ºC toplejši kot v dolgoletnem povprečju, vendar so bili
ravno dnevi okoli štetja najhladnejši, s povprečnimi dnevnimi temperaturami povsod po …