Expansion microscopy (ExM) enables super-resolution imaging of proteins and nucleic
acids on conventional microscopes. However, imaging of details of the organization of lipid …

Sphingolipids are constituents of the cell membrane that perform various tasks as structural
elements and signaling molecules, in addition to regulating many important cellular …

Background Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger
that transduces extracellular signals in virtually all eukaryotic cells. The soluble Beggiatoa …

Expansion microscopy (ExM) is a novel tool to improve the resolution of fluorescence-based
microscopy that has not yet been used to visualize intracellular pathogens. Here we show …

Mitochondria are double membrane bound organelles indispensable for biological processes
such as apoptosis, cell signaling, and the production of many important metabolites, which …

Obligate human pathogenic Neisseria gonorrhoeae are the second most frequent bacterial
cause of sexually transmitted diseases. These bacteria invade different mucosal tissues and …

Cristae architecture is important for the function of mitochondria, the organelles that play the
central role in many cellular processes. The mitochondrial contact site and cristae …

Expansion Microscopy (ExM) is a novel tool improving the resolution of fluorescence microscopy
by linking the sample into a hydrogel that gets physically expanded in water. Previously…

Staphylococcus aureus (S. aureus) is well known to express a plethora of toxins of which
the pore-forming hemolysin A (α-toxin) is the best-studied cytolysin. Pore-forming toxins (PFT) …

Autophagy is a highly conserved catabolic process, degrading unnecessary or damaged
components in the eukaryotic cell to maintain cellular homeostasis, but it is also an intrinsic …