Characterizing the transcriptome of individual cells is fundamental to understanding complex
biological systems. We describe a droplet-based system that enables 3′ mRNA counting …

Plant scientists believe that transpiration—the motion of water from the soil, through a
vascular plant, and into the air—occurs by a passive, wicking mechanism. This mechanism is …

The bone marrow provides spatially and temporally variable signals that impact the behavior
of hematopoietic stem cells (HSCs). While multiple biomolecular signals and bone marrow …

INTRODUCTION: A robust, versatile and compact microreactor has been designed, fabricated
and tested for the labeling of bifunctional chelate conjugated biomolecules (BFC-BM) with …

A pure liquid can reach metastable equilibrium with its subsaturated vapor across an
appropriate membrane. This situation is analogous to osmotic equilibrium: the reduced chemical …

Radiometal-based radiopharmaceuticals, used as imaging and therapeutic agents in nuclear
medicine, consist of a radiometal that is bound to a targeting biomolecule (BM) using a …

Sequencing the genomes of individual cancer cells provides the highest resolution of
intratumoral heterogeneity. To enable high throughput single cell DNA-Seq across thousands of …

A high-throughput screening assay on a microfluidic chip was developed for the determination
of charge variants of monocolonal antibodies (mAbs) in pI range of 7–10. This method …

A 56-year-old man, treated with an angiotensin II receptor antagonist for hypertension,
presented for placement of a cochlear implant during general anesthesia. Intraoperatively, there …

Objectives: To report the occurrence of bradycardia associated with the use of methadone
administered to prevent withdrawal in an infant with physical tolerance following long-term …