The KDM5 family of histone demethylases catalyzes the demethylation of histone H3 on
lysine 4 (H3K4) and is required for the survival of drug-tolerant persister cancer cells (DTPs). …

Chromatin immunoprecipitation and DNA sequencing (ChIP-seq) has been instrumental in
inferring the roles of histone post-translational modifications in the regulation of transcription, …

The process wherein dividing cells exhaust proliferative capacity and enter into replicative
senescence has become a prominent model for cellular aging in vitro. Despite decades of …

The specification of tissue size during development involves the coordinated action of many
signalling pathways responding to organ-intrinsic signals, such as morphogen gradients, …

Mass spectrometry is a powerful alternative to antibody-based methods for the analysis of
histone post-translational modifications (marks). A key development in this approach was the …

Replicative senescence (RS) as a model has become the central focus of research into cellular
aging in vitro. Despite decades of study, this process through which cells cease dividing …

To unravel the causes and effects of aging we can monitor the time-evolution of the aging
process and learn how it is structured by genetic and environmental variation before ultimately …

Energy simulation tools are increasingly used for analysis of energy performance of buildings
and the thermal comfort of their occupants. This paper describes a selection of energy …

… Author links open overlay panel Tobias Maile a b , Vladimir Bazjanac b 2 , Martin Fischer a
1 … Maile [21] describes this conversion process and the developed conversion tool in detail. …

The process of preparing building energy performance simulation (BEPS) models involves
repetitive manual operations that often lead to data losses and errors. As a result, BEPS …