User profiles for Todd Edwards

Todd L. Edwards

Associate Professor of Medicine, Vanderbilt University
Verified email at vanderbilt.edu
Cited by 15651

Factors influencing household recycling behavior

S Oskamp, MJ Harrington, TC Edwards… - Environment and …, 1991 - journals.sagepub.com
To investigate factors encouraging or deterring recycling, telephone interviews were used to
study recycling behavior, attitudes, and knowledge of 221 randomly selected adults in a …

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

…, JB Meigs, PD Reaven, PW Wilson, TL Edwards… - Nature …, 2020 - nature.com
We investigated type 2 diabetes (T2D) genetic susceptibility via multi-ancestry meta-analysis
of 228,499 cases and 1,178,783 controls in the Million Veteran Program (MVP), DIAMANTE…

[HTML][HTML] Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

…, ES Torstenson, KP Shah, T Garcia, TL Edwards… - Nature …, 2018 - nature.com
Scalable, integrative methods to understand mechanisms that link genetic variants with
phenotypes are needed. Here we derive a mathematical expression to compute PrediXcan (a …

Genome‐Wide Association Study Confirms SNPs in SNCA and the MAPT Region as Common Risk Factors for Parkinson Disease

TL Edwards, WK Scott, C Almonte, A Burt… - Annals of human …, 2010 - Wiley Online Library
Parkinson disease (PD) is a chronic neurodegenerative disorder with a cumulative prevalence
of greater than one per thousand. To date three independent genome‐wide association …

Rare and low-frequency coding variants alter human adult height

…, AM Dunning, DF Easton, T Ebeling, TL Edwards… - Nature, 2017 - nature.com
Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

…, A DiVasta, O Dorien, JF Donoghue, T Edwards… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

…, PWF Wilson, PS Tsao, DR Velez Edwards… - Nature …, 2019 - nature.com
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood
pressure to identify genes, tissues, phenomes and medication contexts of blood pressure …

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

…, MJ Bonder, P Chen, A Dehghan, TL Edwards… - Nature …, 2015 - nature.com
We carried out a trans-ancestry genome-wide association and replication study of blood
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …

[PDF][PDF] Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension

…, JA Smith, LR Yanek, YV Sun, TL Edwards… - The American Journal of …, 2015 - cell.com
Genome-wide association studies (GWASs) have identified many genetic variants underlying
complex traits. Many detected genetic loci harbor variants that associate with multiple—…

Identification of genetic susceptibility loci for colorectal tumors in a genome-wide meta-analysis

…, DV Conti, KR Curtis, D Duggan, T Edwards… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Heritable factors contribute to the development of colorectal cancer.
Identifying the genetic loci associated with colorectal tumor formation could elucidate the …