Deep brain stimulation (DBS) is a highly efficacious treatment option for movement disorders
and a growing number of other indications are investigated in clinical trials. To ensure …

Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

Three-dimensional atlases of subcortical brain structures are valuable tools to reference
anatomy in neuroscience and neurology. For instance, they can be used to study the position …

We report the implantation of patient-derived midbrain dopaminergic progenitor cells,
differentiated in vitro from autologous induced pluripotent stem cells (iPSCs), in a patient with …

Longitudinal, remote monitoring of motor symptoms in Parkinson’s disease (PD) could
enable more precise treatment decisions. We developed the Motor fluctuations Monitor for …

The specific loss of midbrain dopamine neurons (mDANs) causes major motor dysfunction in
Parkinson’s disease, which makes cell replacement a promising therapeutic approach 1 , 2 …

Nonlinear registration of individual brain MRI scans to standard brain templates is common
practice in neuroimaging and multiple registration algorithms have been developed and …

A key driver of patients’ well-being and clinical trials for Parkinson’s disease (PD) is the
course that the disease takes over time (progression and prognosis). To assess how genetic …

It is widely reported that the activity of single neurons in visual cortex is correlated with the
perceptual decision of the subject. The strength of this correlation has implications for the …

Objective With a growing appreciation for interindividual anatomical variability and patient‐specific
brain connectivity, advanced imaging sequences offer the opportunity to directly …