Study Objectives Suggested neural correlates of insomnia disorder have been hard to replicate.
Even the most consistent finding, altered white matter microstructure in the anterior limb …

Neuroimaging and genetics studies have advanced our understanding of the neurobiology
of sleep and its disorders. However, individual studies usually have limitations to identifying …

Changes in inhibitory connections are essential for experience-dependent circuit adaptations.
Defects in inhibitory synapses are linked to neurodevelopmental disorders, but the …

Insomnia Disorder (ID) is a prevalent and persistent condition, yet its neural substrate is not
well understood. The cognitive, emotional, and behavioral characteristics of ID suggest that …

Insomnia poses a high risk for depression. Brain mechanisms of sleep and mood improvement
following cognitive behavioural therapy for insomnia remain elusive. This longitudinal …

Background The highest risk of depression is conveyed by insomnia. This risk can be
mitigated by sleep interventions. Understanding brain mechanisms underlying increased …

Background Major depressive disorder is among the most burdening and costly chronic
health hazards. Since its prognosis is poor and treatment effectiveness is moderate at best, …

Objective: Insomnia disorder is the most common sleep disorder. A better understanding of
insomnia-related deviations in the brain could inspire better treatment. Insufficiently …

ABSTRACT Changes in inhibitory connections are essential for experience-dependent circuit
adaptations. Defects in inhibitory synapses are linked to neurodevelopmental disorders, …

Background The COVID-19 pandemic imposes a long period of stress on people worldwide
and has been shown to significantly affect sleep duration across different populations. …