Aneuploidy, chromosomal instability, somatic copy-number alterations, and whole-genome
doubling (WGD) play key roles in cancer evolution and provide information for the complex …

Mutational signatures help to deconvolve the different processes that shape cancer
genomes. A new tool now alleviates some of the persistent challenges in the field.

… Tom L Kaufmann , Tom L Kaufmann … The authors wish it to be known that, in their
opinion, Adam Streck and Tom L Kaufmann should be regarded as Joint First Authors. …

Most computational methods that infer somatic copy number alterations (SCNAs) from bulk
sequencing of DNA analyse tumour samples individually. However, the sequencing of …

Recent experiments with super-resolution live cell microscopy revealed that nonmuscle myosin
II minifilaments are much more dynamic than formerly appreciated, often showing plastic …

Most computational methods that infer somatic copy number alterations (SCNAs) from bulk
sequencing of DNA analyse tumour samples individually. However, the sequencing of …

Telomere maintenance in neuroblastoma is linked to poor outcome and caused by either
TERT activation or through alternative lengthening of telomeres (ALT). In contrast to TERT …

The concept of liabilities of foreignness (LOFs) describes the additional costs that multinational
enterprises have to face relative to their indigenous competitors when operating in …

Background: More epidemiological data about lentigo maligna melanoma (LMM) are required
to define follow-up guidelines. The study focused on recurrence, progression, and overall …

Supply chain relationships are increasingly impacted by the use of the Internet and the adoption
of logistics technology. In this paper we report the results of a large-scale field study of a …