Opportunistic infections, such as aspergillosis, are among the most serious complications
suffered by immunocompromised patients. Aspergillus fumigatus and other pathogenic fungi …

Background Sepsis continues to be a major cause of death, disability, and health-care
expenditure worldwide. Despite evidence suggesting that host genetics can influence sepsis …

The available data support the hypothesis that group A streptococcal impetigo plays a role in
the pathogenesis of RHD. There is considerable scope to investigate this question through …

The possibility of voyaging contact between prehistoric Polynesian and Native American
populations has long intrigued researchers. Proponents have pointed to the existence of New …

The incidence of necrotising soft-tissue infections has increased during recent decades
such that most physicians might see at least one case of these potentially life-threatening …

Ancient DNA from Vanuatu and Tonga dating to about 2,900–2,600 years ago (before
present, BP) has revealed that the "First Remote Oceanians" associated with the Lapita …

We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated
streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, …

The indigenous populations of the South Pacific experience a high burden of rheumatic
heart disease (RHD). Here we report a genome-wide association study (GWAS) of RHD …

Polynesia was settled in a series of extraordinary voyages across an ocean spanning one
third of the Earth 1 , but the sequences of islands settled remain unknown and their timings …

Introduction: Streptococci are a genus of Gram-positive bacteria which cause diverse human
diseases. Many of these species have the potential to cause invasive infection resulting …