Strong association of de novo copy number mutations with autism
…, D Malhotra, J Troge, C Lese-Martin, T Walsh… - Science, 2007 - science.org
We tested the hypothesis that de novo copy number variation (CNV) is associated with autism
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …
Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain
elusive. We hypothesize that individually rare structural variants contribute to the illness. …
elusive. We hypothesize that individually rare structural variants contribute to the illness. …
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
T Walsh, S Casadei, MK Lee… - Proceedings of the …, 2011 - National Acad Sciences
Inherited loss-of-function mutations in BRCA1 and BRCA2 and other tumor suppressor
genes predispose to ovarian carcinomas, but the overall burden of disease due to inherited …
genes predispose to ovarian carcinomas, but the overall burden of disease due to inherited …
Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America
TJ Walsh, EJ Anaissie, DW Denning, R Herbrecht… - Clinical infectious …, 2008 - JSTOR
Aspergillus species have emerged as an important cause of life-threatening infections in
immunocompromised patients. This expanding population is composed of patients with …
immunocompromised patients. This expanding population is composed of patients with …
Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001–2006: overview of the Transplant-Associated Infection …
…, BD Alexander, EJ Anaissie, TJ Walsh… - Clinical infectious …, 2010 - academic.oup.com
Background. The incidence and epidemiology of invasive fungal infections (IFIs), a leading
cause of death among hematopoeitic stem cell transplant (HSCT) recipients, are derived …
cause of death among hematopoeitic stem cell transplant (HSCT) recipients, are derived …
Revision and update of the consensus definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer and the Mycoses …
…, JA Vazquez, C Viscoli, TJ Walsh… - Clinical Infectious …, 2020 - academic.oup.com
Background Invasive fungal diseases (IFDs) remain important causes of morbidity and
mortality. The consensus definitions of the Infectious Diseases Group of the European …
mortality. The consensus definitions of the Infectious Diseases Group of the European …
Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)
…, MG Schuster, R Walker, TJ Walsh… - Clinical Infectious …, 2010 - academic.oup.com
Background. Invasive fungal infections (IFIs) are a major cause of morbidity and mortality
among organ transplant recipients. Multicenter prospective surveillance data to determine …
among organ transplant recipients. Multicenter prospective surveillance data to determine …
[HTML][HTML] Inherited DNA-repair gene mutations in men with metastatic prostate cancer
Background Inherited mutations in DNA-repair genes such as BRCA2 are associated with
increased risks of lethal prostate cancer. Although the prevalence of germline mutations in …
increased risks of lethal prostate cancer. Although the prevalence of germline mutations in …
Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas
KP Pennington, T Walsh, MI Harrell, MK Lee… - Clinical Cancer …, 2014 - AACR
Purpose: Hallmarks of germline BRCA1/2-associated ovarian carcinomas include chemosensitivity
and improved survival. The therapeutic impact of somatic BRCA1/2 mutations and …
and improved survival. The therapeutic impact of somatic BRCA1/2 mutations and …
Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2: National Surgical Adjuvant Breast and Bowel Project (NSABP …
ContextAmong cancer-free women aged 35 years or older, tamoxifen reduced the incidence
of estrogen receptor (ER)–positive but not ER-negative breast cancer. The effect of …
of estrogen receptor (ER)–positive but not ER-negative breast cancer. The effect of …