The tumor microenvironment (TME) is comprised of non-malignant cells that interact with
each other and with cancer cells, critically impacting cancer biology. The TME is complex, and …

Many countries have applied lockdown that helped suppress COVID-19, but with devastating
economic consequences. Here we propose exit strategies from lockdown that provide …

Stress activates a complex network of hormones known as the hypothalamic–pituitary–adrenal
(HPA) axis. The HPA axis is dysregulated in chronic stress and psychiatric disorders, but …

Hormones control the major biological functions of stress response, growth, metabolism, and
reproduction. In animals, these hormones show pronounced seasonality, with different set-…

Graves' disease (GD) and Hashimoto's thyroiditis (HT) are common autoimmune diseases of
the thyroid gland, causing hyperthyroidism and hypothyroidism, respectively. Despite their …

Thyroid disorders are common and often require lifelong hormone replacement. Treating
thyroid disorders involves a fascinating and troublesome delay, in which it takes many weeks …

Bipolar disorder (BD) is marked by fluctuating mood states over months to years, often with
elevated cortisol levels. Elevated cortisol can also trigger mood episodes. Here we combine …

Many autoimmune disorders exhibit flares in which symptoms erupt and then decline, as
exemplified by multiple sclerosis (MS) in its relapsing-remitting form. Existing mathematical …

Major depressive disorder (MDD) is the most common psychiatric disorder. It has a complex
and heterogeneous etiology. Most treatments take weeks to show effects and work well only …

The tumor microenvironment (TME) is composed of various nonmalignant cell types that
interact with each other and with cancer cells, impacting all aspects of cancer biology. The TME …