Outcomes of high-throughput biological experiments are typically interpreted by statistical
testing for enriched gene functional categories defined by the Gene Ontology (GO). The …

Automated annotation of protein function is challenging. As the number of sequenced
genomes rapidly grows, the overwhelming majority of protein products can only be annotated …

Detection of patient zero can give new insights to epidemiologists about the nature of first
transmissions into a population. In this Letter, we study the statistical inference problem of …

Bacteria and Archaea display a variety of phenotypic traits and can adapt to diverse ecological
niches. However, systematic annotation of prokaryotic phenotypes is lacking. We have …

Codon usage bias in prokaryotic genomes is largely a consequence of background substitution
patterns in DNA, but highly expressed genes may show a preference towards codons …

The present paper demonstrates the antiproliferative ability and structure−activity relationships
(SAR) of 14 crown and aza-crown ether analogues on five tumor-cell types. The most …

Widespread use of herbicides results in the global increase in weed resistance. The
rotational use of herbicides according to their modes of action (MoAs) and discovery of novel …

P-glycoprotein (P-gp, MDR1) is a promiscuous drug efflux pump of substantial pharmacological
importance. Taking advantage of large-scale cytotoxicity screening data involving 60 …

Hematological and biochemical tests are widely used for assessment of health status and
diagnosis of disease in domestic animals. They are almost indispensible in health …

Motivation Increasing efforts are being made in the field of machine learning to advance the
learning of robust and accurate models from experimentally measured data and enable …