The neuropharmacology of impulsive behaviour

T Pattij, LJMJ Vanderschuren - Trends in pharmacological sciences, 2008 - cell.com
Impulsivity is a heterogenous phenomenon encompassing several behavioural phenomena
that can be dissociated neuroanatomically as well as pharmacologically. Impulsivity is …

Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats

L Diergaarde, T Pattij, I Poortvliet, F Hogenboom… - Biological …, 2008 - Elsevier
BACKGROUND: Although heavy smoking has been associated with impulsivity in humans,
it is not clear whether poor impulse control represents a risk factor in the etiology of nicotine …

[HTML][HTML] The relationship between impulsive choice and impulsive action: a cross-species translational study

…, W van den Brink, DJ Veltman, TJ de Vries, T Pattij… - PloS one, 2012 - journals.plos.org
Maladaptive impulsivity is a core symptom in various psychiatric disorders. However, there
is only limited evidence available on whether different measures of impulsivity represent …

Involvement of dopamine D1 and D2 receptors in the nucleus accumbens core and shell in inhibitory response control

T Pattij, MCW Janssen, LJMJ Vanderschuren… - …, 2007 - Springer
Rationale Impaired inhibitory control over behavior is a key feature in various psychiatric
disorders, and recent studies indicated an important role for dopamine D 1 and D 2 receptors …

Stress-induced hyperthermia and anxiety: pharmacological validation

B Olivier, T Zethof, T Pattij, M Van Boogaert… - European journal of …, 2003 - Elsevier
When mammals, including man, are confronted with a stressful event, their core body
temperature rises, stress-induced hyperthermia. In mice, the stress-induced hyperthermia …

Compulsivity in obsessive–compulsive disorder and addictions

M Figee, T Pattij, I Willuhn, J Luigjes… - European …, 2016 - Elsevier
Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

[HTML][HTML] Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats

…, TJ De Vries, AB Smit, T Pattij - …, 2009 - nature.com
Adolescence is a developmental period, during which the brain and particularly medial
prefrontal cortical (mPFC) regions thereof have not fully matured. Because epidemiological data …

[PDF][PDF] Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum

…, RA Abdullah, AL Loriaux, D Schetters, T Pattij… - Neuron, 2012 - cell.com
Transient increases in nucleus accumbens (NAc) dopamine concentration are observed
when animals are presented with motivationally salient stimuli and are theorized to energize …

Individual differences in male rat ejaculatory behaviour: searching for models to study ejaculation disorders

T Pattij, TR De Jong, A Uitterdijk… - European Journal of …, 2005 - Wiley Online Library
In addition to investigating sexual function in rats that display normal ejaculatory behaviour,
studying rats that are either ‘hyposexual’ or ‘hypersexual’ may provide important insights into …

Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility

JR Homberg, T Pattij, MCW Janssen… - European Journal of …, 2007 - Wiley Online Library
Impulsivity and aggression have been suggested to inversely correlate with central serotonin
(5‐HT) levels in a trait‐like manner. However, this relationship is far from straightforward. In …