[HTML][HTML] Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started
to circulate among humans around December 2019, and it is now widespread as a global …
to circulate among humans around December 2019, and it is now widespread as a global …
Expedited approach toward the rational design of noncovalent SARS-CoV-2 main protease inhibitors
…, F Zhang, X Zhang, M Ba, T Szeto… - Journal of medicinal …, 2021 - ACS Publications
The main protease (M pro ) of SARS-CoV-2 is a validated antiviral drug target. Several M pro
inhibitors have been reported with potent enzymatic inhibition and cellular antiviral activity, …
inhibitors have been reported with potent enzymatic inhibition and cellular antiviral activity, …
Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and a FlipGFP-based reporter assay
…, JA Townsend, Y Hu, X Meng, T Szeto… - ACS central …, 2021 - ACS Publications
The papain-like protease (PL pro ) of SARS-CoV-2 is a validated antiviral drug target.
Through a fluorescence resonance energy transfer-based high-throughput screening and …
Through a fluorescence resonance energy transfer-based high-throughput screening and …
Rational design of hybrid SARS-CoV-2 main protease inhibitors guided by the superimposed cocrystal structures with the peptidomimetic inhibitors GC-376, telaprevir …
SARS-CoV-2 main protease (M pro ) is a cysteine protease that mediates the cleavage of
viral polyproteins and is a validated antiviral drug target. M pro is highly conserved among all …
viral polyproteins and is a validated antiviral drug target. M pro is highly conserved among all …
Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronaviruses
As the COVID-19 pandemic continues to unfold, the morbidity and mortality are increasing
daily. Effective treatment for SARS-CoV-2 is urgently needed. We recently discovered four …
daily. Effective treatment for SARS-CoV-2 is urgently needed. We recently discovered four …
[HTML][HTML] Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronaviruses in cell culture
As the COVID-19 pandemic continues to fold out, the morbidity and mortality are increasing
daily. Effective treatment for SARS-CoV-2 is urgently needed. We recently discovered four …
daily. Effective treatment for SARS-CoV-2 is urgently needed. We recently discovered four …
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease (preprint)
C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto… - 2020 - pesquisa.bvsalud.org
A novel coronavirus SARS-CoV-2, also called novel coronavirus 2019 (nCoV-19), started to
circulate among humans around December 2019, and it is now widespread as a global …
circulate among humans around December 2019, and it is now widespread as a global …
Prevalence of ocular manifestations and visual outcomes in patients with herpes zoster ophthalmicus
Purpose: To investigate the prevalence of ocular manifestations and visual outcomes in
patients with herpes zoster ophthalmicus (HZO). Methods: Consecutive cases diagnosed with …
patients with herpes zoster ophthalmicus (HZO). Methods: Consecutive cases diagnosed with …
[BOOK][B] Dynamic traffic assignment: formulations, properties, and extensions
WY Szeto - 2003 - search.proquest.com
… Representing traffic dynamics as side constraints explicitly is cumbersome and makes
solutions difficult to be obtained efficiently (Lo and Szeto, 2002a). Modeling the traffic-flow …
solutions difficult to be obtained efficiently (Lo and Szeto, 2002a). Modeling the traffic-flow …
A Student Perspective on the Effectiveness of PASS in Seminar Courses: A Mixed-Method Study
WM Szeto, KM Li, VJ Wu, IKT Wong… - Journal of Peer …, 2022 - ro.uow.edu.au
The General Education Foundation (GEF) Programme, consisting of two seminar courses,
namely “In Dialogue with Humanity” and “In Dialogue with Nature,” has been a common core …
namely “In Dialogue with Humanity” and “In Dialogue with Nature,” has been a common core …