User profiles for Tomokazu Tamura

Tomokazu Tamura

Junior Associate Professor
Verified email at pop.med.hokudai.ac.jp
Cited by 2037

[HTML][HTML] Characterization of H7N9 influenza A viruses isolated from humans

…, RP de Vries, S Shichinohe, M Okamatsu, T Tamura… - Nature, 2013 - nature.com
Avian influenza A viruses rarely infect humans; however, when human infection and subsequent
human-to-human transmission occurs, worldwide outbreaks (pandemics) can result. …

SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

…, D Kenney, I Castello-Serrano, S Suzuki, T Tamura… - Elife, 2021 - elifesciences.org
Many enveloped viruses induce multinucleated cells (syncytia), reflective of membrane
fusion events caused by the same machinery that underlies viral entry. These syncytia are …

Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B

T Tamura, Y Sakoda, F Yoshino, T Nomura… - Journal of …, 2012 - Am Soc Microbiol
Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a
highly contagious disease of pigs. There are numerous CSFV strains that differ in virulence, …

Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1–4

T Tamura, J Zhang, V Madan, A Biswas… - Emerging Microbes & …, 2022 - Taylor & Francis
Dengue is caused by four genetically distinct viral serotypes, dengue virus (DENV) 1-4.
Following transmission by Aedes mosquitoes, DENV can cause a broad spectrum of clinically …

[HTML][HTML] Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

T Tamura, J Ito, K Uriu, J Zahradnik, I Kida… - Nature …, 2023 - nature.com
In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified, and XBB is
spreading rapidly around the world. Our phylogenetic analyses suggested that XBB …

Virological characteristics of the SARS-CoV-2 Omicron BA. 2 subvariants, including BA. 4 and BA. 5

I Kimura, D Yamasoba, T Tamura, N Nao, T Suzuki… - Cell, 2022 - cell.com
After the global spread of the SARS-CoV-2 Omicron BA.2, some BA.2 subvariants, including
BA.2.9.1, BA.2.11, BA.2.12.1, BA.4, and BA.5, emerged in multiple countries. Our statistical …

[HTML][HTML] Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ. 1.1 variant

…, S Deguchi, L Wang, S Lytras, T Tamura… - Nature …, 2023 - nature.com
In late 2022, various Omicron subvariants emerged and cocirculated worldwide. These
variants convergently acquired amino acid substitutions at critical residues in the spike protein, …

[HTML][HTML] Characterization of miR-122-independent propagation of HCV

…, D Okuzaki, S Yamamoto, T Tamura… - PLoS …, 2017 - journals.plos.org
miR-122, a liver-specific microRNA, is one of the determinants for liver tropism of hepatitis C
virus (HCV) infection. Although miR-122 is required for efficient propagation of HCV, we …

[PDF][PDF] Virological characteristics of the SARS-CoV-2 BA. 2.86 variant

T Tamura, K Mizuma, H Nasser, S Deguchi… - Cell Host & Microbe, 2024 - cell.com
In late 2023, several SARS-CoV-2 XBB descendants, notably EG.5.1, were predominant
worldwide. However, a distinct SARS-CoV-2 lineage, the BA.2.86 variant, also emerged. BA.…

[HTML][HTML] saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern

…, MR Hassett, Y Masuta, H Ode, T Tamura… - Nature …, 2023 - nature.com
Several vaccines have been widely used to counteract the global pandemic caused by
SARS-CoV-2. However, due to the rapid emergence of SARS-CoV-2 variants of concern (VOCs), …