User profiles for Tomoya Hino

Tomoya Hino

Tottori University
Verified email at bio.tottori-u.ac.jp
Cited by 3098

Crystal structure of human indoleamine 2,3-dioxygenase: Catalytic mechanism of O2 incorporation by a heme-containing dioxygenase

H Sugimoto, S Oda, T Otsuki, T Hino… - Proceedings of the …, 2006 - National Acad Sciences
Human indoleamine 2,3-dioxygenase (IDO) catalyzes the cleavage of the pyrrol ring of l-Trp
and incorporates both atoms of a molecule of oxygen (O 2 ). Here we report on the x-ray …

Structural Basis of Biological N2O Generation by Bacterial Nitric Oxide Reductase

T Hino, Y Matsumoto, S Nagano, H Sugimoto… - Science, 2010 - science.org
Nitric oxide reductase (NOR) is an iron-containing enzyme that catalyzes the reduction of
nitric oxide (NO) to generate a major greenhouse gas, nitrous oxide (N 2 O). Here, we report …

G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody

T Hino, T Arakawa, H Iwanari, T Yurugi-Kobayashi… - Nature, 2012 - nature.com
Hino, TA and TS purified and crystallized the receptor/Fab-fragment complex. SW, ADC
and … Hino solved and refined the structure. T. Hino, SI and TM wrote the manuscript and all …

[HTML][HTML] Molecular structure and function of bacterial nitric oxide reductase

T Hino, S Nagano, H Sugimoto, T Tosha… - Biochimica et Biophysica …, 2012 - Elsevier
The crystal structure of the membrane-integrated nitric oxide reductase cNOR from
Pseudomonas aeruginosa was determined. The smaller NorC subunit of cNOR is comprised of 1 …

Crystal structure of the anion exchanger domain of human erythrocyte band 3

…, Y Alguel, H Iwanari, H Hatae, M Iwata, Y Abe, T Hino… - Science, 2015 - science.org
Anion exchanger 1 (AE1), also known as band 3 or SLC4A1, plays a key role in the removal
of carbon dioxide from tissues by facilitating the exchange of chloride and bicarbonate …

Structure and mechanism of the mammalian fructose transporter GLUT5

…, M Coincon, Y Sato, H Abe, Y Nakada-Nakura, T Hino… - Nature, 2015 - nature.com
The altered activity of the fructose transporter GLUT5, an isoform of the facilitated-diffusion
glucose transporter family, has been linked to disorders such as type 2 diabetes and obesity. …

Crystal structures of the human adiponectin receptors

…, T Terada, N Ohsawa, M Hato, S Ogasawara, T Hino… - Nature, 2015 - nature.com
Adiponectin stimulation of its receptors, AdipoR1 and AdipoR2, increases the activities of 5′
AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor (…

Permporometry characterization of microporous ceramic membranes

T Tsuru, T Hino, T Yoshioka, M Asaeda - Journal of Membrane Science, 2001 - Elsevier
An evaluation of nano-order pore size of membranes was carried out using permporometry,
the basic principle of which is based on capillary condensation of vapor and the blocking …

Crystal structure of quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus

Y Matsumoto, T Tosha, AV Pisliakov, T Hino… - Nature structural & …, 2012 - nature.com
The structure of quinol-dependent nitric oxide reductase (qNOR) from G. stearothermophilus,
which catalyzes the reduction of NO to produce the major ozone-depleting gas N 2 O, has …

[HTML][HTML] NO reduction by nitric-oxide reductase from denitrifying bacterium Pseudomonas aeruginosa: characterization of reaction intermediates that appear in the …

H Kumita, K Matsuura, T Hino, S Takahashi… - Journal of Biological …, 2004 - ASBMB
Nitric-oxide reductase (NOR) of a denitrifying bacterium catalyzes NO reduction to N 2 O at
the binuclear catalytic center consisting of high spin heme b 3 and non-heme Fe B . The …