Comparative analysis of SARS‐CoV‐2 Omicron BA. 2.12. 1 and BA. 5.2 variants

…, Y Xie, H Zhang, Z Qin, H Sun, TY Wang… - Journal of Medical …, 2023 - Wiley Online Library
The initial severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron
subvariants, BA.1 and BA.2, are being progressively displaced by BA.5 in many countries. To …

Aminopeptidase N is an entry co-factor triggering porcine deltacoronavirus entry via an endocytotic pathway

YL Yang, J Liu, TY Wang, M Chen, G Wang… - Journal of …, 2021 - Am Soc Microbiol
Porcine deltacoronavirus (PDCoV) is a recently discovered coronavirus that poses a potential
threat to the global swine industry. Although we know that aminopeptidase N (APN) is …

[HTML][HTML] Genomic analyses reveal that partial sequence of an earlier pseudorabies virus in China is originated from a Bartha-vaccine-like strain

…, JC Gao, TY Wang, K Zhao, XB Chang, Q Wang… - Virology, 2016 - Elsevier
Pseudorabies virus (PRV), the causative agent of Aujeszky׳s disease, has gained increased
attention in China in recent years as a result of the outbreak of emergent pseudorabies. …

Live attenuated pseudorabies virus developed using the CRISPR/Cas9 system

YD Tang, JT Liu, TY Wang, TQ An, MX Sun, SJ Wang… - Virus research, 2016 - Elsevier
Currently, pseudorabies virus (PRV) variant strains are outbreaking in China; these variants
belong to genotype II PRV. The traditional Bartha-K61 vaccine has failed to provide …

[HTML][HTML] Evasion of antiviral innate immunity by porcine reproductive and respiratory syndrome virus

TY Wang, MX Sun, HL Zhang, G Wang… - Frontiers in …, 2021 - frontiersin.org
Innate immunity is the front line for antiviral immune responses and bridges adaptive immunity
against viral infections. However, various viruses have evolved many strategies to evade …

[HTML][HTML] Evaluating angiotensin-converting enzyme 2-mediated SARS-CoV-2 entry across species

…, J Sun, YY Zhang, TY Wang, MX Sun, MH Wang… - Journal of Biological …, 2021 - ASBMB
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents
a global threat, and the interaction between the virus and angiotensin-converting enzyme 2 (…

Neuropilin-1 facilitates pseudorabies virus replication and viral glycoprotein B promotes its degradation in a furin-dependent manner

M Chen, MH Wang, XG Shen, H Liu, YY Zhang… - Journal of …, 2022 - Am Soc Microbiol
Pseudorabies virus (PRV), which is extremely infectious and can infect numerous mammals,
has a risk of spillover into humans. Virus–host interactions determine viral entry and …

[HTML][HTML] SARS-CoV-2 hijacks macropinocytosis to facilitate its entry and promote viral spike–mediated cell-to-cell fusion

YY Zhang, R Liang, SJ Wang, ZW Ye, TY Wang… - Journal of Biological …, 2022 - ASBMB
Revealing the mechanisms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
entry and cell-to-cell spread might provide insights for understanding the underlying …

[HTML][HTML] Pseudorabies virus UL24 abrogates tumor necrosis factor alpha-induced NF-κB activation by degrading P65

TY Wang, YL Yang, C Feng, MX Sun, JM Peng, ZJ Tian… - Viruses, 2020 - mdpi.com
The transcription factor NF-κB plays a critical role in diverse biological processes. The NF-κB
pathway can be activated by incoming pathogens and then stimulates both innate and …

[HTML][HTML] Porcine alveolar macrophage CD163 abundance is a pivotal switch for porcine reproductive and respiratory syndrome virus infection

TY Wang, YG Liu, L Li, G Wang, HM Wang, HL Zhang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Porcine reproductive and respiratory syndrome virus (PRRSV) is a problematic virus that is
difficult to control. The principal target cells for PRRSV infection are porcine alveolar …