Cancer cells driven by the Ras oncogene scavenge unsaturated fatty acids (FAs) from their
environment to counter nutrient stress. The human group X secreted phospholipase A 2 (…

Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to acquire …

Lipid droplets have a unique structure among organelles consisting of a dense hydrophobic
core of neutral lipids surrounded by a single layer of phospholipids decorated with various …

Lipid droplets are cytosolic fat storage organelles present in most eukaryotic cells. Long
regarded merely as inert fat reservoirs, they are now emerging as major regulators of cellular …

Lipid droplets are fat storage organelles present in most eukaryotic cells. They consist of a
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …

Secreted phospholipases A 2 (sPLA 2 s) hydrolyse cell and lipoprotein phospholipid membranes
to release free fatty acids and lysophospholipids, and can also bind to specific proteins…

Ammodytin L (AtnL) is a Ser-49 secretory phospholipase A 2 (sPLA 2 ) homologue with
myotoxic activity. By analogy to the Lys-49 sPLA 2 myotoxins, AtnL has been predicted to be …

When the brain is in a pathological state, the content of lipid droplets (LDs), the lipid storage
organelles, is increased, particularly in glial cells, but rarely in neurons. The biology and …

Background Alterations in lipid metabolism are inherent to the metabolic transformations that
support tumorigenesis. The relationship between the synthesis, storage and use of lipids …

Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic kingdom.
They have a central role in regulating lipid metabolism and undergo a dynamic turnover …