The growing prevalence of counterfeit products worldwide poses serious threats to economic
security and human health. Developing advanced anti-counterfeiting materials with …

Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar
cells examined individually has prompted interest in obtaining parallel methylome data. We …

Aging is associated with significant changes in the hematopoietic system, including increased
inflammation, impaired hematopoietic stem cell (HSC) function, and increased incidence …

Elucidation of the identity and diversity of mechanisms that sustain long-term human blood
cell production remains an important challenge. Previous studies indicate that, in adult mice, …

The superior properties of diamond have made it a versatile platform for many promising
applications in a wide range of areas. Thus, various methods, like chemical vapor deposition (…

We present Epiclomal, a probabilistic clustering method arising from a hierarchical mixture
model to simultaneously cluster sparse single-cell DNA methylation data and impute missing …

Complex microbial communities, eg, biofilms residing in our oral cavity, have recognized
clinical significance, as they are typically the main cause for infections. Particularly, they show …

Global heterochromatin reduction, which is one of the hallmarks of senescent cells, is
associated with reduced transposable element repression and increased risk of chromatin …

Widefield quantum diamond microscopy (WQDM) based on Kohler illumination has been
widely adopted in the field of quantum sensing; however, practical applications are still limited …

Nucleoside analogues are effective antiviral agents, and the continuous emergence of
pathogenic viruses demands the development of novel and structurally diverse analogues. Here, …