For the first time, three-dimensional images of the newborn infant brain have been generated
using measurements of transmitted light. A 32-channel time-resolved imaging system was …

The first 1,000 days of life are a critical window of vulnerability to exposure to socioeconomic
and health challenges (ie poverty/undernutrition). The Brain Imaging for Global Health (…

OBJECTIVE. The absence of cerebral autoregulation in preterm infants has been associated
with adverse outcome, but its bedside assessment in the immature brain is problematic. We …

Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral
blood flow (CBF) relatively constant across changes in cerebral perfusion pressure (CPP). …

Purpose With growing evidence that rare single gene disorders present in the neonatal period,
there is a need for rapid, systematic, and comprehensive genomic diagnoses in ICUs to …

Objective To determine if it is possible to stabilise the cerebral oxygenation of extremely
preterm infants monitored by cerebral near infrared spectroscopy (NIRS) oximetry. Design …

There is a need to ensure standardization of training and clinical practice guidelines, with
quality assurance systems in place to maintain safe dissemination of this practice. There are …

Background Studies have shown that complex structural variants (cxSVs) contribute to human
genomic variation and can cause Mendelian disease. We aimed to identify cxSVs relevant …

Near-infrared spectroscopy-derived regional tissue oxygen saturation of haemoglobin (rStO
2 ) reflects venous oxygen saturation. If cerebral metabolism is stable, rStO 2 can be used as …

Induced haemodynamic and blood oxygenation changes occurring within the brain of a
ventilated newborn infant have been imaged in three dimensions using optical tomography. …