[HTML][HTML] α-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy

…, H Egeblad, P Bross, TA Kruse… - The Journal of …, 1999 - Am Soc Clin Investig
We identified the α-cardiac actin gene (ACTC) as a novel disease gene in a pedigree
suffering from familial hypertrophic cardiomyopathy (FHC). Linkage analyses excluded all the …

[PDF][PDF] Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

…, P Leon, NB Freimer, H Ewald, TA Kruse… - The American Journal of …, 2003 - cell.com
Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage.
The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD …

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

…, G Glendon, AE Toland, UB Jensen, TA Kruse… - Nature …, 2015 - nature.com
Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC)
susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and …

Long non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor-positive primary breast cancer

…, M Bak, S Cold, M Burton, MJ Larsen, TA Kruse - Breast cancer research …, 2013 - Springer
Expression of HOX transcript antisense intergenic RNA (HOTAIR)—a long non-coding RNA—has
been examined in a variety of human cancers, and overexpression of HOTAIR is …

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

…, TL Chan, FJ Couch, DE Goldgar, TA Kruse… - Human …, 2018 - Wiley Online Library
The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been reported
in single populations, with the majority of reports focused on White in Europe and North …

[HTML][HTML] Evaluation of nine somatic variant callers for detection of somatic mutations in exome and targeted deep sequencing data

AB Krøigård, M Thomassen, AV Lænkholm, TA Kruse… - PloS one, 2016 - journals.plos.org
Next generation sequencing is extensively applied to catalogue somatic mutations in cancer,
in research settings and increasingly in clinical settings for molecular diagnostics, guiding …

Reduced expression of nuclear-encoded genes involved in mitochondrial oxidative metabolism in skeletal muscle of insulin-resistant women with polycystic ovary …

V Skov, D Glintborg, S Knudsen, T Jensen, TA Kruse… - Diabetes, 2007 - Am Diabetes Assoc
Insulin resistance in skeletal muscle is a major risk factor for the development of type 2
diabetes in women with polycystic ovary syndrome (PCOS). In patients with type 2 diabetes, …

Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders

…, M Nyegaard, A Haagerup, J Vestbo, TA Kruse… - Thorax, 2008 - thorax.bmj.com
Background: Toll-like receptors (TLRs) are structurally and functionally related and play
important roles in the innate and adaptive immune system. By genome scanning, evidence of …

Hereditary breast cancer: clinical, pathological and molecular characteristics

…, AM Gerdes, TA Kruse - Breast cancer: basic …, 2014 - journals.sagepub.com
Pathogenic mutations in BRCA1 or BRCA2 are only detected in 25% of families with a
strong history of breast cancer, though hereditary factors are expected to be involved in the …

[HTML][HTML] Cloning, expression, and chromosome mapping of human galectin-7

…, HH Rasmussen, T Flint, P Gromov, TA Kruse… - Journal of Biological …, 1995 - Elsevier
The galectins are a family of β-galactoside-binding proteins implicated in modulating cell-cell
and cell-matrix interactions. Here we report the cloning and expression of a novel member …