User profiles for Toshifumi Tsukahara

Toshifumi Tsukahara

Japan Advanced Institute of Science and Technology
Verified email at jaist.ac.jp
Cited by 6208

[HTML][HTML] A view of pre-mRNA splicing from RNase R resistant RNAs

H Suzuki, T Tsukahara - International journal of molecular sciences, 2014 - mdpi.com
During pre-mRNA splicing, exons in the primary transcript are precisely connected to generate
an mRNA. Intron lariat RNAs are formed as by-products of this process. In addition, some …

Mutations in the integrin α7 gene cause congenital myopathy

…, E Ozawa, Y Goto, I Nonaka, T Tsukahara… - Nature …, 1998 - nature.com
The basal lamina of muscle fibers plays a crucial role in the development and function of
skeletal muscle. An important laminin receptor in muscle is integrin α7β1D. Integrin β1 is …

Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide

K Arahata, S Ishiura, T Ishiguro, T Tsukahara, Y Suhara… - Nature, 1988 - nature.com
Duchenne muscular dystrophy (DMD) is a debilitating X-linked muscle disease. We have
used sequence information from complementary DNA clones, derived from the gene that is …

Emerin deficiency at the nuclear membrane in patients with Emery-Dreif uss muscular dystrophy

…, J Kawada, R Okada, YK Hayashi, T Tsukahara… - Nature …, 1996 - nature.com
Mutations in the STA gene at the Xq28 locus have been found in patients with X-linked
Emery-Dreifuss muscular dystrophy (EDMD). This gene encodes a hitherto unknown protein …

The m6A methyltransferase METTL3 contributes to Transforming Growth Factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the …

…, A Ishimura, T Takino, M Sakari, T Tsukahara… - Biochemical and …, 2020 - Elsevier
N6-Methyladenosine (m6A) is the most common internal chemical modification of mRNAs
involved in many pathological processes including various cancers. In this study, we …

Distribution of cathepsins B and H in rat tissues and peripheral blood cells

E KOMINAMI, T TSUKAHARA, Y BANDO… - The Journal of …, 1985 - academic.oup.com
The concentrations of cathepsins B and H in various tissues and peripheral blood cells of rats
were determined by means of sensitive immunoassays. The minimum detectable amounts …

Multi-wall carbon nanotubes (MWCNTs)-doped polypyrrole DNA biosensor for label-free detection of genetically modified organisms by QCM and EIS

…, TV Hoang, DT Quang, DQ Khieu, T Tsukahara… - Talanta, 2010 - Elsevier
In this paper, we describe DNA electrochemical detection for genetically modified organism (GMO)
based on multi-wall carbon nanotubes (MWCNTs)-doped polypyrrole (PPy). DNA …

Biosyntheses and processing of lysosomal cysteine proteinases in rat macrophages

E Kominami, T Tsukahara, K Hara, N Katunuma - FEBS letters, 1988 - Elsevier
The intracellular processing and release of three lysosomal cysteine proteinases, cathepsin
B, H and L, by rat peritoneal macrophages were investigated by pulse-chase experiments. …

Unfolding the apoptotic mechanism of antioxidant enriched-leaves of Tabebuia pallida (lindl.) miers in EAC cells and mouse model

…, M Rashid, MG Sadik, MA Reza, T Tsukahara… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Tabebuia pallida (Lindl.) Miers (T. pallida) is a well-known
native Caribbean medicinal plant. The leaves and barks of T. pallida are used as traditional …

Dystrophin diagnosis: comparison of dystrophin abnormalities by immunofluorescence and immunoblot analyses.

…, LM Kunkel, S Ishiura, T Tsukahara… - Proceedings of the …, 1989 - National Acad Sciences
Immunoblot characterization and immunofluorescence localization of dystrophin are
presented for 76 human patients with various neuromuscular diseases. Normal dystrophin (shown …