[HTML][HTML] A mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidase

H Yamamoto, Y Tobisawa, T Inubushi, F Irie… - Journal of Biological …, 2017 - ASBMB
Hyaluronan (HA) is an extremely large polysaccharide (glycosaminoglycan) involved in many
cellular functions. HA catabolism is thought to involve the initial cleavage of extracellular …

Low-intensity pulsed ultrasound reduces the inflammatory activity of synovitis

…, K Yamamoto-Nagata, T Katsura, T Inubushi… - Annals of biomedical …, 2011 - Springer
The purpose of this study was to examine the effect of low-intensity pulsed ultrasound (LIPUS)
on the cell proliferation and growth of synovial membrane cells stimulated with …

Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

H Furusho, M Miyauchi, H Hyogo, T Inubushi… - Journal of …, 2013 - Springer
Background We investigated the effects of dental infection with Porphyromonas gingivalis (Pg),
an important periodontal pathogen, on NASH progression, by feeding mice a high fat diet …

[HTML][HTML] Dental Infection of Porphyromonas gingivalis Induces Preterm Birth in Mice

M Ao, M Miyauchi, H Furusho, T Inubushi, M Kitagawa… - PLoS …, 2015 - journals.plos.org
Background Epidemiological studies have revealed a link between dental infection and
preterm birth or low birth weight (PTB/LBW), however, the underlying mechanisms remain …

Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

…, H Yasui, T Taira, S Morikawa, T Inubushi… - … medicine and cellular …, 2009 - hindawi.com
Astrocytes, one of the predominant types of glial cells, function as both supportive and
metabolic cells for the brain. Under cerebral ischemia/reperfusion-induced oxidative conditions, …

Low-intensity pulsed ultrasound activates integrin-mediated mechanotransduction pathway in synovial cells

…, S Horiuchi, T Nakamura, M Karima, T Inubushi… - Annals of biomedical …, 2014 - Springer
Low-intensity pulsed ultrasound (LIPUS) suppresses synovial hyperplasia and synovial cell
proliferation characterized for rheumatoid arthritis, but the molecular mechanisms remain …

[HTML][HTML] Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma

C Chea, M Miyauchi, T Inubushi… - PLoS …, 2018 - journals.plos.org
Background Lactoferrin (LF), a member of the transferrin family, recently has been demonstrated
to have anticancer effects on various cancers including oral squamous cell carcinoma (…

[HTML][HTML] Molecular mechanisms of the inhibitory effects of bovine lactoferrin on lipopolysaccharide-mediated osteoclastogenesis

T Inubushi, A Kawazoe, M Miyauchi, Y Kudo… - Journal of Biological …, 2012 - ASBMB
Lactoferrin (LF) is an important modulator of the immune response and inflammation. It has
also been implicated in the regulation of bone tissue. In our previous study we demonstrated …

Cementoblast response to low-and high-intensity ultrasound

DA Dalla-Bona, E Tanaka, T Inubushi, H Oka… - Archives of Oral …, 2008 - Elsevier
OBJECTIVE: It has been shown that ultrasound stimulation accelerates repair of orthodontically
induced root resorption. However, the mechanism of such adaptive change is still unclear…

Ultrasound stimulation attenuates resorption of tooth root induced by experimental force application

T Inubushi, E Tanaka, EB Rego, J Ohtani, A Kawazoe… - Bone, 2013 - Elsevier
Root resorption is an adverse outcome of orthodontic tooth movement. However, there have
been no available approaches for the protection and repair of root resorption. The aim of …