Vitamin K occurs in the natural world in several forms, including a plant form, phylloquinone
(PK), and a bacterial form, menaquinones (MKs). In many species, including humans, PK is …

There are two forms of naturally occurring vitamin K, phylloquinone and the menaquinones.
Phylloquinone (vitamin K 1 ) is a major type (>90%) of dietary vitamin K, but its …

Fibroblast growth factor 23 (FGF23) exerts its effect by binding to its cognate FGF receptor 1
(FGFR1) in the presence of its co-receptor Klotho. Parathyroid glands express both FGFR1 …

The molecular basis of the immunomodulatory properties of 1α, 25-dihydroxyvitamin D 3 (1α,
25 (OH) 2 D 3) remains elusive. We demonstrate here that 1α, 25 (OH) 2 D 3-mediated …

Recently, it was revealed that 1α,25-dihydroxyvitamin D 3 (1α,25(OH) 2 D 3 ) and 24R,25-dihydroxyvitamin
D 3 (24,25(OH) 2 D 3 ) were metabolized to their respective epimers of the …

Several reports indicate an important role for vitamin K in bone health as well as blood
coagulation. However, the current Adequate Intakes (AI) might not be sufficient for the …

Mice have the ability to convert dietary phylloquinone (vitamin K 1 ) into menaquinone-4 (vitamin
K 2 ) and store the latter in tissues. A prenyltransferase enzyme, UbiA prenyltransferase …

We report here the development of a precise and sensitive method to determine 25-hydroxyvitamin
D (25-OH-D 2 / -D 3 ) in human plasma using high-perfomance liquid …

1α,25-Dihydroxyvitamin D 3 (1α,25-D 3 ) has potent antiproliferative and anti-invasive
properties in vitro in cancer cells. However, its calcemic effect in vivo limits its therapeutic …

Sensitive quantification method for fat-soluble vitamins in human breast milk by liquid
chromatography–tandem mass spectrometry was developed. Vitamins A, D and E were extracted …