User profiles for Tracy Augustine
 | Tracy AugustinePost-Doctoral Research Fellow at Sidra Medicine, Doha, Qatar Verified email at sidra.org Cited by 98 |
HSP70 binding protein 1 (HspBP1) suppresses HIV-1 replication by inhibiting NF-κB mediated activation of viral gene expression
HIV-1 efficiently hijacks host cellular machinery and exploits a plethora of host–viral interactions
for its successful survival. Identifying host factors that affect susceptibility or resistance to …
for its successful survival. Identifying host factors that affect susceptibility or resistance to …
[HTML][HTML] Cyclin F/FBXO1 interacts with HIV-1 viral infectivity factor (Vif) and restricts progeny virion infectivity by ubiquitination and proteasomal degradation of Vif …
Cyclin F protein, also known as FBXO1, is the largest among all cyclins and oscillates in the
cell cycle like other cyclins. Apart from being a G 2 /M cyclin, cyclin F functions as the …
cell cycle like other cyclins. Apart from being a G 2 /M cyclin, cyclin F functions as the …
[HTML][HTML] Microbial dysbiosis tunes the immune response towards allergic disease outcomes
The hygiene hypothesis has been popularized as an explanation for the rapid increase in
allergic disease observed over the past 50 years. Subsequent epidemiological studies have …
allergic disease observed over the past 50 years. Subsequent epidemiological studies have …
High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines
Knowledge of the mechanisms underpinning the development of protective immunity
conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus …
conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus …
[HTML][HTML] Asthma and the Missing Heritability Problem: Necessity for Multiomics Approaches in Determining Accurate Risk Profiles
T Augustine, MA Al-Aghbar, M Al-Kowari… - Frontiers in …, 2022 - frontiersin.org
Asthma is ranked among the most common chronic conditions and has become a significant
public health issue due to the recent and rapid increase in its prevalence. Investigations …
public health issue due to the recent and rapid increase in its prevalence. Investigations …
Gut microbial influences on the adaptive immune system and the development of cow milk allergy
T Augustine, F Badri, S Murugesan… - Qatar Medical …, 2022 - qscience.com
Allergic diseases constitute significant health and economic issues in both developed and
developing nations, with epidemiological studies demonstrating a rapid increase in the global …
developing nations, with epidemiological studies demonstrating a rapid increase in the global …
High temporal resolution transcriptomic profiling delineates distinct patterns of interferon response following Covid-19 mRNA vaccination and SARS-CoV2 infection
…, A Ballestrero, M Bassetti, BP Hejblum, T Augustine… - bioRxiv, 2021 - biorxiv.org
ABSTRACT Knowledge of the factors contributing to the development of protective immunity
after vaccination with COVID-19 mRNA vaccines is fragmentary. Thus we employed high- …
after vaccination with COVID-19 mRNA vaccines is fragmentary. Thus we employed high- …
Dendritic cell activation and screening for key molecular signatures required for the induction of allergic responses
M Ameen Al-Aghbar, T Augustine… - Qatar Medical …, 2022 - qscience.com
The chain of events that leads to the sensitization of the immune system to environmental
antigens, resulting in the onset of allergic disease, has been studied in great detail over the …
antigens, resulting in the onset of allergic disease, has been studied in great detail over the …
[PDF][PDF] Cyclin F/FBXO1 interacts with HIV-1 Vif and restricts progeny virion infectivity by ubiquitination and proteasomal degradation of Vif through SCFCyclin F E3 …
Cyclin F, also known as FBXO1, is the largest among all cyclins which oscillates in the cell
cycle like other cyclins. Apart from being a G2/M cyclin, Cyclin F functions as the substrate …
cycle like other cyclins. Apart from being a G2/M cyclin, Cyclin F functions as the substrate …
HSP70 binding protein 1 (HspBP1) suppresses HIV-1 replication by inhibiting NF- B mediated activation of viral gene expression
…, S Khan S, P Rawat P, T Augustine… - Nucleic Acids …, 2015 - nccs.sciencecentral.in
HIV-1 efficiently hijacks host cellular machinery and exploits a plethora of host–viral interactions
for its successful survival. Identifying host factors that affect susceptibility or resistance to …
for its successful survival. Identifying host factors that affect susceptibility or resistance to …