User profiles for Tramy T. Nguyen

Tramy Nguyen

Raytheon BBN Technologies
Verified email at raytheon.com
Cited by 822

Robustness and reproducibility of simple and complex synthetic logic circuit designs using a DBTL loop

…, J Beal, B Bartley, T Mitchell, TT Nguyen… - Synthetic …, 2023 - academic.oup.com
Computational tools addressing various components of design–build–test–learn (DBTL)
loops for the construction of synthetic genetic networks exist but do not generally cover the …

Round trip: an automated pipeline for experimental design, execution, and analysis

…, M DeHaven, J Beal, B Bartley, TT Nguyen… - ACS Synthetic …, 2022 - ACS Publications
Synthetic biology is a complex discipline that involves creating detailed, purpose-built
designs from genetic parts. This process is often phrased as a Design-Build-Test-Learn loop, …

Computational prediction of synthetic circuit function across growth conditions

…, B Bartley, TT Nguyen, N Roehner, T Mitchell… - bioRxiv, 2022 - biorxiv.org
A challenge in the design and construction of synthetic genetic circuits is that they will operate
within biological systems that have noisy and changing parameter regimes that are largely …

[PDF][PDF] Asynchronous Genetic Circuit Design

TT Nguyen - 2019 - geneticlogiclab.org
Synthetic biology is applying engineering concepts to biological processes to enable genetic
circuit designs, among other applications. As more biological parts are being discovered, it …

[PDF][PDF] Intent parser: a tool for codifying experiment design

T Nguyen, N Walczak, J Beal… - … Workshop on Bio …, 2020 - jakebeal.github.io
2 INTENT PARSER ARCHITECTURE Fundamentally, the Intent Parser acts as a link between
a user-friendly document editor (in this case Google Docs) and a repository of formal de …

SBML Level 3: an extensible format for the exchange and reuse of biological models

…, T Nguyen, A Palmisano, JB Pettit, T Pfau… - Molecular systems …, 2020 - embopress.org
Abstract Systems biology has experienced dramatic growth in the number, size, and
complexity of computational models. To reproduce simulation results and reuse models, …

iBioSim 3: A Tool for Model-Based Genetic Circuit Design

L Watanabe, T Nguyen, M Zhang, Z Zundel… - ACS synthetic …, 2018 - ACS Publications
The iBioSim tool has been developed to facilitate the design of genetic circuits via a model-based
design strategy. This paper illustrates the new features incorporated into the tool for …

A computational workflow for the automated generation of models of genetic designs

G Misirli, T Nguyen, JA McLaughlin… - ACS synthetic …, 2018 - ACS Publications
Computational models are essential to engineer predictable biological systems and to scale
up this process for complex systems. Computational modeling often requires expert …

Sharing structure and function in biological design with SBOL 2.0

…, M Pocock, M Bissell, C Madsen, T Nguyen… - ACS synthetic …, 2016 - ACS Publications
The Synthetic Biology Open Language (SBOL) is a standard that enables collaborative
engineering of biological systems across different institutions and tools. SBOL is developed …

Design of asynchronous genetic circuits

T Nguyen, TS Jones, P Fontanarrosa… - Proceedings of the …, 2019 - ieeexplore.ieee.org
… The work of T. Nguyen, JV Mante, and CJ Myers was supported by the National Science
Foundation under Grant CCF-1748200. The work of T. …