User profiles for Trang T. Le

Trang T. Le

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 2879

Scaling tree-based automated machine learning to biomedical big data with a feature set selector

TT Le, W Fu, JH Moore - Bioinformatics, 2020 - academic.oup.com
Motivation Automated machine learning (AutoML) systems are helpful data science assistants
designed to scan data for novel features, select appropriate supervised learning models …

[HTML][HTML] A nonlinear simulation framework supports adjusting for age when analyzing BrainAGE

TT Le, RT Kuplicki, BA McKinney, HW Yeh… - Frontiers in aging …, 2018 - frontiersin.org
Several imaging modalities, including T1-weighted structural imaging, diffusion tensor
imaging, and functional MRI can show chronological age related changes. Employing machine …

[HTML][HTML] Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: an international multi-centre observational cohort study

…, D Kraska, AK Krishnamurthy, S L'Yi, TT Le… - …, 2023 - thelancet.com
Background While acute kidney injury (AKI) is a common complication in COVID-19, data
on post-AKI kidney function recovery and the clinical factors associated with poor kidney …

PMLB v1. 0: an open-source dataset collection for benchmarking machine learning methods

JD Romano, TT Le, W La Cava, JT Gregg… - …, 2022 - academic.oup.com
Motivation Novel machine learning and statistical modeling studies rely on standardized
comparisons to existing methods using well-studied benchmark datasets. Few tools exist that …

Pitfalls in brain age analyses

ER Butler, A Chen, R Ramadan, TT Le, K Ruparel… - 2021 - Wiley Online Library
Over the past decade, there has been an abundance of research on the difference between
age and age predicted using brain features, which is commonly referred to as the “brain age …

Structural and practical identifiability analysis of outbreak models

N Tuncer, TT Le - Mathematical biosciences, 2018 - Elsevier
Estimating the reproduction number of an emerging infectious disease from an epidemiological
data is becoming more essential in evaluating the current status of an outbreak. However…

[HTML][HTML] Interoception and mental health: a roadmap

…, J Kroll, R Kuplicki, R Lapidus, T Le… - Biological psychiatry …, 2018 - Elsevier
Interoception refers to the process by which the nervous system senses, interprets, and
integrates signals originating from within the body, providing a moment-by-moment mapping of …

Statistical inference relief (STIR) feature selection

TT Le, RJ Urbanowicz, JH Moore, BA McKinney - Bioinformatics, 2019 - academic.oup.com
Motivation Relief is a family of machine learning algorithms that uses nearest-neighbors to
select features whose association with an outcome may be due to epistasis or statistical …

International analysis of electronic health records of children and youth hospitalized with COVID-19 infection in 6 countries

…, T Ganslandt, LX Garmire, T Gradinger… - JAMA network …, 2021 - jamanetwork.com
Importance Additional sources of pediatric epidemiological and clinical data are needed to
efficiently study COVID-19 in children and youth and inform infection prevention and clinical …

[HTML][HTML] Identification and replication of RNA-Seq gene network modules associated with depression severity

TT Le, J Savitz, H Suzuki, M Misaki, TK Teague… - Translational …, 2018 - nature.com
Genomic variation underlying major depressive disorder (MDD) likely involves the interaction
and regulation of multiple genes in a network. Data-driven co-expression network module …