User profiles for Travis Loya
 | Travis LoyaEmory University Verified email at emory.edu Cited by 158 |
A genetic screen for terminator function in yeast identifies a role for a new functional domain in termination factor Nab3
The yeast IMD2 gene encodes an enzyme involved in GTP synthesis. Its expression is
controlled by guanine nucleotides through a set of alternate start sites and an intervening …
controlled by guanine nucleotides through a set of alternate start sites and an intervening …
[HTML][HTML] A network of interdependent molecular interactions describes a higher order Nrd1-Nab3 complex involved in yeast transcription termination
TJ Loya, TW O'Rourke, N Degtyareva… - Journal of Biological …, 2013 - ASBMB
Nab3 and Nrd1 are yeast heterogeneous nuclear ribonucleoprotein (hnRNP)-like proteins
that heterodimerize and bind RNA. Genetic and biochemical evidence reveals that they are …
that heterodimerize and bind RNA. Genetic and biochemical evidence reveals that they are …
[HTML][HTML] Recent advances in understanding transcription termination by RNA polymerase II
Transcription termination is a fundamental process in which RNA polymerase ceases RNA
chain extension and dissociates from the chromatin template, thereby defining the end of the …
chain extension and dissociates from the chromatin template, thereby defining the end of the …
[HTML][HTML] Yeast Nab3 protein contains a self-assembly domain found in human heterogeneous nuclear ribonucleoprotein-C (hnRNP-C) that is necessary for …
Nab3 is an RNA-binding protein whose function is important for terminating transcription by
RNA polymerase II. It co-assembles with Nrd1, and the resulting heterodimer of these …
RNA polymerase II. It co-assembles with Nrd1, and the resulting heterodimer of these …
Amyloid-like assembly of the low complexity domain of yeast Nab3
Termination of transcription of short non-coding RNAs is carried out in yeast by the Nab3-Nrd1-Sen1
complex. Nab3 and Nrd1 are hnRNP-like proteins that dimerize and bind RNA with …
complex. Nab3 and Nrd1 are hnRNP-like proteins that dimerize and bind RNA with …
[HTML][HTML] The hnRNP-like Nab3 termination factor can employ heterologous prion-like domains in place of its own essential low complexity domain
Many RNA-binding proteins possess domains with a biased amino acid content. A common
property of these low complexity domains (LCDs) is that they assemble into an ordered …
property of these low complexity domains (LCDs) is that they assemble into an ordered …
[HTML][HTML] Nab3's localization to a nuclear granule in response to nutrient deprivation is determined by its essential prion-like domain
Ribonucleoprotein (RNP) granules are higher order assemblies of RNA, RNA-binding proteins,
and other proteins, that regulate the transcriptome and protect RNAs from environmental …
and other proteins, that regulate the transcriptome and protect RNAs from environmental …
Imaging and tracking mRNA in live mammalian cells via fluorogenic photoaffinity labeling
Cellular RNA labeling using light-up aptamers that bind to and activate fluorogenic molecules
has gained interest in recent years as an alternative to protein-based RNA labeling …
has gained interest in recent years as an alternative to protein-based RNA labeling …
[PDF][PDF] RNA polymerase II [version 1; peer review: 2 approved]
Transcription termination is a fundamental process in which RNA polymerase ceases RNA
chain extension and dissociates from the chromatin template, thereby defining the end of the …
chain extension and dissociates from the chromatin template, thereby defining the end of the …
Investigating the structure and function of a prion-like domain in the Nrd1-Nab3-Sen1 transcription termination system
T Loya - 2019 - etd.library.emory.edu
From a single genome, yeast must adapt their transcriptional profile to respond to or initiate
changes in the cell. A key step in this process is transcriptional termination, which in yeast is …
changes in the cell. A key step in this process is transcriptional termination, which in yeast is …