A biofilm is an organized, resilient group of microbes in which individual cells acquire
properties, such as drug resistance, that are distinct from those observed in suspension cultures. …

When transcription regulatory networks are compared among distantly related eukaryotes, a
number of striking similarities are observed: a larger-than-expected number of genes, …

Blood-feeding mosquitoes survive by feeding on nectar for metabolic energy but require a
blood meal to develop eggs. Aedes aegypti females must accurately discriminate blood and …

We examine how different transcriptional network structures can evolve from an ancestral
network. By characterizing how the ancestral mode of gene regulation for genes specific to a-…

Epistasis—the non-additive interactions between different genetic loci—constrains evolutionary
pathways, blocking some and permitting others 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 . For biological …

Sequence-specific DNA-binding proteins are among the most important classes of gene
regulatory proteins, controlling changes in transcription that underlie many aspects of biology. In …

Predatory animals pursue prey in a noisy sensory landscape, deciding when to continue or
abandon their chase. The mosquito Aedes aegypti is a micropredator that first detects …

Changes in both the coding sequence of transcriptional regulators and in the cis-regulatory
sequences recognized by these regulators have been implicated in the evolution of …

The invasive Argentine ant (Linepithema humile) is established worldwide and displaces
native ant species. In northern California, however, the native winter ant (Prenolepis imparis) …

10.7554/eLife.37563.001 Convergent evolutionary events in independent lineages provide
an opportunity to understand why evolution favors certain outcomes over others. We studied …