Cas13 nucleases are a class of programmable RNA-targeting CRISPR effector proteins that
are capable of silencing target gene expression in mammalian cells. Here, we demonstrate …

Beta genus human papillomaviruses (β-HPVs) cause cutaneous squamous cell carcinomas
(cSCCs) in a subset of immunocompromised patients. However, β-HPVs are not necessary …

CRISPR technology has demonstrated broad utility for controlling target gene expression;
however, there remains a need for strategies capable of modulating expression via the …

An abnormal expansion of a GGGGCC hexanucleotide repeat in the C9ORF72 gene is the
most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal …

CRISPR technology has demonstrated broad utility for controlling target gene expression;
however, there remains a need for strategies capable of modulating expression via the …

Beta genus human papillomaviruses (β-HPVs) are associated with cutaneous squamous
cell carcinomas (cSCCs) in a subset of immunocompromised patients. Although β-HPVs are …

Multiple coronaviruses have emerged independently in the past 20 years that cause lethal
human diseases. Although vaccine development targeting these viruses has been …

While vaccines are vital for preventing COVID-19 infections, it is critical to develop new
therapies to treat patients who become infected. Pharmacological targeting of a host factor …

… Tristan. All these populations are exploited commercially. The catch, processing and export
of J. tristani is the most important economic activity for the inhabitants of Tristan … the Tristan da …

… Flaked stone was analysed by Arden Cruickshank and Andrew McAlister. Four stone
types were identified: obsidian, chert, basalt and greywacke, with obsidian and chert further …