Metal-hydride hydrogen atom transfer (MHAT) functionalizes alkenes with predictable branched
(Markovnikov) selectivity. The breadth of these transformations has been confined to π-…

Breast cancers possess fundamentally altered metabolism that fuels their pathogenicity.
While many metabolic drivers of breast cancers have been identified, the metabolic pathways …

Many natural products that show therapeutic activities are often difficult to synthesize or isolate
and have unknown targets, hindering their development as drugs. Identifying druggable …

Chemical genetic screening of small-molecule libraries has been a promising strategy for
discovering unique and novel therapeutic compounds. However, identifying the targets of lead …

Small molecules that modulate the 14-3-3 protein–protein interaction (PPI) network represent
valuable therapeutics and tool compounds. However, access has been lost to 14-3-3 PPI …

Parthenolide, a natural product from the feverfew plant and member of the large family of
sesquiterpene lactones, exerts multiple biological and therapeutic activities including anti-…

Pd 0 ‐catalyzed Mizoroki–Heck reactions traditionally exhibit poor reactivity with polysubstituted,
unbiased alkenes. Intermolecular reactions with simple, all‐carbon tetrasubstituted …

Pd(0)-catalyzed, non-chain-walking Mizoroki-Heck reactions exhibit poor reactivity with
polysubsti- tuted, unbiased alkenes. Intermolecular reactions with simple, all-carbon …

… We address the Huffman case, and the Hu-Tucker case follows immediately because for
monotonically ordered distributions the Huffman algorithm solves the Hu-Tucker problem. For a …

The Dark Energy Survey Collaboration has completed construction of the Dark Energy Camera
(DECam), a 3 square degree, 570 Megapixel CCD camera which will be mounted on the …