User profiles for Tulika Tulika

Tulika Prakash Srivastava

Associate Professor, SBS, IIT Mandi, HP, India
Verified email at iitmandi.ac.in
Cited by 2833

[HTML][HTML] Advances in antibody phage display technology

…, A Ljungars, C Rimbault, CV Sørensen, T Tulika… - Drug Discovery …, 2022 - Elsevier
Phage display technology can be used for the discovery of antibodies for research, diagnostic,
and therapeutic purposes. In this review, we present and discuss key parameters that can …

[HTML][HTML] Protecting the aging genome

MA Petr, T Tulika, LM Carmona-Marin… - Trends in Cell …, 2020 - cell.com
Mounting evidence suggests that DNA damage plays a central role in aging. Multiple tiers of
defense have evolved to reduce the accumulation of DNA damage, including reducing …

[HTML][HTML] AHA: AI-guided tool for the quantification of venom-induced haemorrhage in mice

…, WM Laprade, A Sánchez, T Tulika… - Frontiers in Tropical …, 2022 - frontiersin.org
Venom-induced haemorrhage constitutes a severe pathology in snakebite envenomings,
especially those inflicted by viperid species. In order to both explore venom activity accurately …

[HTML][HTML] Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper

…, MB Pucca, M Fiebig, FA Cerni, T Tulika… - Nature …, 2024 - nature.com
Improved therapies are needed against snakebite envenoming, which kills and permanently
disables thousands of people each year. Recently developed neutralizing monoclonal …

Deep Mining of Complex Antibody Phage Pools

T Tulika, A Ljungars - Phage Display: Methods and Protocols, 2023 - Springer
An important, and rapidly growing class of drugs are antibodies which can be discovered
through phage display technology. In this technique, antibodies are typically first enriched …

Phage display assisted discovery of a pH‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library

T Tulika, RW Pedersen, C Rimbault, S Ahmadi… - Protein …, 2023 - Wiley Online Library
Recycling IgG antibodies bind to their target antigen at physiological pH in the blood stream
and release them upon endocytosis when pH levels drop, allowing the IgG antibodies to be …

Ketones facilitate transcriptional resolution of secondary DNA structures in premature aging

MA Petr, LM Carmona-Marin, T Tulika, S Kristensen… - bioRxiv, 2022 - biorxiv.org
There is currently no established intervention for Cockayne syndrome, a disease characterized
by progressive early onset neurodegeneration with features of premature aging. Here, …

ALOHA: AI-guided tool for the quantification of venom-induced haemorrhage in mice

TP Jenkins, WM Laprade, A Sánchez, T Tulika… - bioRxiv, 2022 - biorxiv.org
Venom-induced haemorrhage constitutes a severe pathology in snakebite envenomings,
especially those inflicted by viperid species. In order to both explore venom compositions …

[HTML][HTML] Pharmaceutical potential of aquatic plant Pistia stratiotes (L.) and Eichhornia crassipes

T Tulika, A Mala - Journal of plant sciences, 2014 - aaphysiol.com
Pistia stratiotes L. commonly known as water lettuce belongs to Araceae. It has been used
in various medicines for the treatment of eczema, leprosy, ulcers, piles, stomach disorder, …

[HTML][HTML] Enterotype variations of the healthy human gut microbiome in different geographical regions

F Mobeen, V Sharma, P Tulika - Bioinformation, 2018 - ncbi.nlm.nih.gov
Enterotypes are used for classifying individuals based on the gut microbiome. A number of
studies are available to find the Enterotypes in healthy individuals; however, most of them …