Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
…, AH Skogholt, JA Smith, AE Taylor, C Turman… - Nature …, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …
The power of genetic diversity in genome-wide association studies of lipids
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use 1 . Despite …
prevalence worldwide owing to different dietary patterns and medication use 1 . Despite …
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
…, P Kraft, DJ Hunter, KL Penney, C Turman… - Nature …, 2021 - nature.com
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
[HTML][HTML] Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
…, HM Stringham, T Tanaka, A Teumer, C Turman… - Nature …, 2022 - nature.com
Although physical activity and sedentary behavior are moderately heritable, little is known
about the mechanisms that influence these traits. Combining data for up to 703,901 …
about the mechanisms that influence these traits. Combining data for up to 703,901 …
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
…, PL Møller, L Stefansdottir, G Galarneau, C Turman… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
…, C Barbieri, A Cavadino, JE Chavarro, C Turman… - Nature …, 2016 - nature.com
The genetic architecture of human reproductive behavior—age at first birth (AFB) and number
of children ever born (NEB)—has a strong relationship with fitness, human development, …
of children ever born (NEB)—has a strong relationship with fitness, human development, …
The Mediterranean diet, plasma metabolome, and cardiovascular disease risk
Aims To investigate whether metabolic signature composed of multiple plasma metabolites
can be used to characterize adherence and metabolic response to the Mediterranean diet …
can be used to characterize adherence and metabolic response to the Mediterranean diet …
[HTML][HTML] Identification of nine new susceptibility loci for endometrial cancer
…, AJ Swerdlow, E Tham, J Trovik, C Turman… - Nature …, 2018 - nature.com
Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract
in developed countries. Through genome-wide association studies (GWAS), we have …
in developed countries. Through genome-wide association studies (GWAS), we have …
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
…, P Suchon, MH Chen, C Turman… - Blood, The Journal …, 2019 - ashpublications.org
Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To
advance our understanding of the biology contributing to VTE, we conducted a genome-wide …
advance our understanding of the biology contributing to VTE, we conducted a genome-wide …
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
…, AR Thurik, NJ Timpson, C Turman… - Nature human …, 2021 - nature.com
Age at first sexual intercourse and age at first birth have implications for health and
evolutionary fitness. In this genome-wide association study (age at first sexual intercourse, N = …
evolutionary fitness. In this genome-wide association study (age at first sexual intercourse, N = …