[HTML][HTML] Evaluation of DNA extraction methods on individual helminth egg and larval stages for whole-genome sequencing

…, B Softley, E Thiele, PT Ouakou, JV Tushabe… - Frontiers in …, 2019 - frontiersin.org
Whole-genome sequencing is being rapidly applied to the study of helminth genomes, including
de novo genome assembly, population genetics, and diagnostic applications. Although …

[HTML][HTML] Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot …

TJ Vianney, DJ Berger, SR Doyle… - PLoS Neglected …, 2022 - journals.plos.org
Populations within schistosomiasis control areas, especially those in Africa, are recommended
to receive regular mass drug administration (MDA) with praziquantel (PZQ) as the main …

[HTML][HTML] Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in …

…, G Nabakooza, M Nakibuule, JV Tushabe… - Frontiers in …, 2020 - frontiersin.org
Background: BCG has low efficacy in tropical countries. We hypothesized that maternal
latent Mycobacterium tuberculosis (M.tb) infection (LTBI) results in fetal tolerance to …

Schistosoma mansoni‐specific immune responses and allergy in Uganda

…, G O'Hara, B Nerima, D Kizito, JV Tushabe… - Parasite …, 2018 - Wiley Online Library
Low allergy‐related disease ( ARD ) prevalence in low‐income countries may be partly
attributed to helminth infections. In the Schistosoma mansoni (Sm)‐endemic Lake Victoria …

Does intensive treatment select for praziquantel resistance in high-transmission settings? parasitological trends and treatment efficacy within a cluster-randomized trial

JV Tushabe, L Lubyayi, J Sserubanja… - Open forum …, 2020 - academic.oup.com
Background Praziquantel mass drug administration (MDA) is recommended in
schistosomiasis-endemic areas. Animal models demonstrate Schistosoma parasite resistance to …

Genome-wide analysis of Schistosoma mansoni reveals population structure and praziquantel drug selection pressure within Ugandan hot-spot communities

TJ Vianney, DJ Berger, SR Doyle… - bioRxiv, 2022 - biorxiv.org
Populations within schistosomiasis control areas, especially those in Africa, are recommended
to receive regular mass drug administration (MDA) with praziquantel (PZQ) as the main …

Bacterial and fungal contaminants in mycobacterium tuberculosis cultures at national tuberculosis referral laboratory-Kampala

TJ Vianney, K Esther, IJ Stanley - 2017 - nru.uncst.go.ug
Aim: This study was aimed at identification of fungal and bacterial contaminants in Tuberculosis
cultures at the Uganda National Reference Laboratory (NTRL). Methods: The cultures …

[PDF][PDF] This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and …

MRG NKURUNUNGI, G Nkurunungi, J Kabagenyi… - core.ac.uk
Low allergy-related disease (ARD) prevalence in low-income countries may be partly attributed
to helminth infections. In the Schistosoma mansoni (Sm)-endemic Lake Victoria islands (…

Do helminth infections underpin urban‐rural differences in risk factors for allergy‐related outcomes?

G Nkurunungi, L Lubyayi, SA Versteeg… - Clinical & …, 2019 - Wiley Online Library
Background It is proposed that helminth exposure protects against allergy‐related disease,
by mechanisms that include disconnecting risk factors (such as atopy) from effector …

[HTML][HTML] Anthelminthic treatment receipt and its predictors in Lake Victoria fishing communities, Uganda: Intervention coverage results from the LaVIISWA cluster …

H Akurut, RE Sanya, L Lubyayi… - PLoS Neglected …, 2020 - journals.plos.org
Background Mass drug administration (MDA) is a cornerstone of control of parasitic helminths.
In schistosomiasis-endemic areas with >50% of school-aged children infected, community…