[HTML][HTML] Atlas of type 2 dopamine receptors in the human brain: Age and sex dependent variability in a large PET cohort

T Malén, T Karjalainen, J Isojärvi, A Vehtari… - NeuroImage, 2022 - Elsevier
Background The dopamine system contributes to a multitude of functions ranging from
reward and motivation to learning and movement control, making it a key component in goal-…

The effect of sex and perpetrator–victim relationship on perceptions of domestic homicide

LC Karlsson, T Malén, JK Kaakinen… - Journal of …, 2021 - journals.sagepub.com
Previous research on how stereotypes affect perceptions of intimate partner violence and
domestic homicide has found that violence committed by men is perceived as more severe and …

Brain glucose metabolism and aging: a 5-year longitudinal study in a large positron emission tomography cohort

K Pak, T Malén, S Santavirta, S Shin, HY Nam… - Diabetes …, 2023 - Am Diabetes Assoc
Brain glucose metabolism, assessed by 18F-fluorodeoxyglucose (FDG) positron emission
tomography (PET), can be used to quantify neuronal activity in the human brain (1). Aging is …

[HTML][HTML] Alterations in type 2 dopamine receptors across neuropsychiatric conditions: A large-scale PET cohort

T Malén, S Santavirta, S De Maeyer, J Tuisku… - NeuroImage: Clinical, 2024 - Elsevier
Purpose Aberrant dopaminergic function is linked with motor, psychotic, and affective
symptoms, but studies have typically compared a single patient group with healthy controls …

[PDF][PDF] Aerobic Fitness Is Associated with Cerebral μ-Opioid Receptor Activation in Healthy Humans

…, K Kalliokoski, J Hirvonen, T Malen… - Medicine & Science …, 2022 - exerciseismedicine.gr
METHODS Subjects. The Ethics Committee of the Hospital District of Southwest Finland
approved the study protocol, and the study was conducted in accordance with the Declaration of …

Age and sex dependent variability of type 2 dopamine receptors in the human brain: A large-scale PET cohort

T Malén, T Karjalainen, J Isojärvi, A Vehtari… - bioRxiv, 2021 - biorxiv.org
BACKGROUND The dopamine system contributes to a multitude of functions ranging from
reward and motivation to learning and movement control, making it a key component in goal-…

[HTML][HTML] Decoding brain basis of laughter and crying in natural scenes

L Nummenmaa, T Malèn, S Nazari-Farsani, K Seppälä… - NeuroImage, 2023 - Elsevier
Laughter and crying are universal signals of prosociality and distress, respectively. Here we
investigated the functional brain basis of perceiving laughter and crying using naturalistic …

[HTML][HTML] μ-opioid receptor availability is associated with sex drive in human males

L Nummenmaa, P Jern, T Malén, T Kantonen… - Cognitive, Affective, & …, 2022 - Springer
The endogenous mu-opioid receptor (MOR) system modulates a multitude of social and
reward-related functions, and exogenous opiates also influence sex drive in humans and …

Taxonomy for human social perception

S Santavirta, T Malen, A Erdemli, L Nummenmaa - bioRxiv, 2023 - biorxiv.org
In everyday life, humans encounter complex social situations that need to be encoded
effectively to allow seamless interaction with others. Yet, principles organizing the perception of …

Seasonal variation in D2/3 dopamine receptor availability in the human brain

L Sun, T Malen, J Tuisku, V Kaasinen, J Hietala… - bioRxiv, 2023 - biorxiv.org
Brain functional and physiological plasticity is essential to combat dynamic environmental
challenges. The rhythmic in vivo dopamine signaling pathway, which regulates emotion, …